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A reticulocyte count that is high, normal or low will aid with the classification process. A high reticulocyte count signifies that bone marrow processes are normal. A low reticulocyte count would signify there is a problem at the level of the bone marrow, which produce the stem cells. Acute blood loss would result in a high reticulocyte count ...
The reticulocyte production index (RPI) or corrected reticulocyte count (CRC) represents the true significance of the absolute reticulocyte count to provide some reflection of erythropoietic demand and supply. The immature reticulocyte fraction (IRF) goes a step further to cast more light on the same question. [citation needed]
The reticulocyte index (RI) should be between 0.5% and 2.5% for a healthy individual. [8] RI < 0.5% with anemia indicates maturation disorder, meaning loss of red blood cells, but also decreased production of reticulocytes (i.e., an inadequate response to correct the anemia) and therefore red blood cells. [2]
A reticulocyte percentage that is higher than "normal" can be a sign of anemia, but this depends on the health of a person's bone marrow. Calculating the reticulocyte production index is an important step in understanding whether or not the reticulocyte count is appropriate to the situation. This is often a more important question than whether ...
Hematocrit levels that are too high or too low can indicate a blood disorder, dehydration, or other medical conditions. [4] An abnormally low hematocrit may suggest anemia, a decrease in the total amount of red blood cells, while an abnormally high hematocrit is called polycythemia. [5] Both are potentially life-threatening disorders.
Reticulocyte count - Reticulocytes are elevated when the infant is producing more blood to combat anemia. [1] A rise in the retic count can mean that an infant may not need additional transfusions. [33] Low retic is observed in infants treated with IUT and in those with HDN from anti-Kell. [13]
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The most common causes of microcytic anemia are iron deficiency (due to inadequate dietary intake, gastrointestinal blood loss, or menstrual blood loss), thalassemia, sideroblastic anemia or chronic disease. In iron deficiency anemia (microcytic anemia), it can be as low as 60 to 70 femtolitres