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Desmopressin, sold under the trade name DDAVP among others, is a medication used to treat diabetes insipidus, bedwetting, hemophilia A, von Willebrand disease, and high blood urea levels. [1] In hemophilia A and von Willebrand disease, it should only be used for mild to moderate cases. [ 1 ]
US drug regulators have banned using desmopressin nasal sprays for treating bedwetting since the oral form is considered safer. DDAVP is most efficient in children with nocturnal polyuria (nocturnal urine production greater than 130% of expected bladder capacity for age) and normal bladder reservoir function (maximum voided volume greater than ...
Vasopressin agonists are used therapeutically in various conditions, and its long-acting synthetic analogue desmopressin is used in conditions featuring low vasopressin secretion, as well as for control of bleeding (in some forms of von Willebrand disease and in mild haemophilia A) and in extreme cases of bedwetting by children.
Tofranil – a tricyclic antidepressant used to treat depression, anxiety, agitation, panic disorder and bedwetting; Topamax – an anticonvulsant used to treat epilepsy and migraine headaches; Trileptal (oxcarbazepine) – an anticonvulsant used as a mood stabilizer
The most prominent vasopressin analogues include desmopressin (dDAVP), terlipressin, and selepressin, each with distinct pharmacological profiles and clinical uses. Desmopressin, a V2 receptor agonist, is primarily used for treating diabetes insipidus and certain bleeding disorders. [ 3 ]
"A typical dose of caffeine (100 mg) can be consumed up to 4 hours prior to bedtime without significant effect on subsequent sleep. To mitigate caffeine-induced sleep disruptions, it is ...
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