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Primidone, sold under various brand names (including Mysoline), is a barbiturate medication that is used to treat partial and generalized seizures [7] and essential tremors. [8] It is taken by mouth. [7] Its common side effects include sleepiness, poor coordination, nausea, and loss of appetite. [7] Severe side effects may include suicide and ...
This medication has shown the same beneficial effects in reducing tremors as propranolol and is recommended for use based on guidelines from the American Academy of Neurology and the MDS Task Force on Tremor. The initial dose of primidone is recommended at 25 mg per day and should be increased up to the maximum dose of 250 mg per day.
It has been demonstrated in essential tremor animal models that the food additive 1-octanol suppresses tremors induced by harmaline, and decreases the amplitude of essential tremor for about 90 minutes. [20] Two of the most valuable drug treatments for essential tremor are propranolol, a beta blocker, and primidone, an anticonvulsant ...
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Essential tremor may be treated with beta blockers (such as propranolol and nadolol) or primidone, an anticonvulsant Cerebellar tremor symptoms may decrease with the application of alcohol (ethanol) or benzodiazepine medications, both of which carry some risk of dependence or addiction
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The U.S. Capitol is seen at sunset on the eve of the first anniversary of the January 6, 2021 attack on the building, on Capitol Hill in Washington, U.S., January 5, 2022.
"A comparison of primidone, propranolol, and placebo in essential tremor, using quantitative analysis". Journal of Neurology, Neurosurgery & Psychiatry . 49 (1): 64–8.
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