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Aqueous Cream BP, also known as sorbolene, is a light, hydrocarbon-based emulsion, which is officially registered in the British Pharmacopoeia and categorised by the British National Formulary as a non-proprietary emollient preparation. [1]
A container with cream. Topical cream formulation is an emulsion semisolid dosage form that is used for skin external application. Most of the topical cream formulations contain more than 20 per cent of water and volatiles and/or less than 50 per cent of hydrocarbons, waxes, or polyethylene glycols as the vehicle for external skin application. [1]
Bottle of E45 cream. E45 cream is a skin care product created in 1952 and currently marketed by Karo Pharma. It is a moisturizer. Its active ingredients are lanolin, white soft paraffin and liquid paraffin. E45 was initially only available in hospitals, but was later made available for retail.
Cream. A cream is a preparation usually for application to the skin.Creams for application to mucous membranes such as those of the rectum or vagina are also used. Creams may be considered pharmaceutical products, since even cosmetic creams are manufactured using techniques developed by pharmacy and unmedicated creams are highly used in a variety of skin conditions (dermatoses).
Ointments are more occlusive than aqueous creams, which are more occlusive than lotion. [5] Water loss through the skin is normally about 4–8 g/(m 2 ⋅h). A layer of petrolatum applied to normal skin can reduce that loss by 50–75% for several hours. [4] Oils naturally produced by the human body moisturize through this same mechanism. [2]
Reviewers' main criticism applies not to the cream itself, but the container: "Love the cream, but the straw to the pump is way too short. Leaves about 1/3 of the product," one user said.
[5] [7] The solvent that is used as a dispersion medium can be aqueous, organic, inorganic, or a system of different solvents. [5] Topical gels are used as a contact or transport medium for active drugs to act on [4] or through the skin. [9] The active drug molecules are entwined into the 3D mesh of the gel and delivered to the site of action.
Three classes of barrier creams are used: water repellent creams, water-soluble creams, and creams designed for special applications. [4] Barrier creams may contain substances such as zinc oxide, talc or kaolin to layer over the skin. [5] For hand care they are designed to protect against the harm from detergents and other irritants. [6]