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Bactericidal for both Gram-positive and Gram-negative organisms and therefore useful for empiric broad-spectrum antibacterial coverage. (Notes: MRSA resistance to this class. All are active against Pseudomonas aeruginosa except ertapenem.) Gastrointestinal upset and diarrhea; Nausea; Seizures; Headache; Rash and allergic reactions
Narrow-spectrum antibiotics have low propensity to induce bacterial resistance and are less likely to disrupt the microbiome (normal microflora). [3] On the other hand, indiscriminate use of broad-spectrum antibiotics may not only induce the development of bacterial resistance and promote the emergency of multidrug-resistant organisms, but also cause off-target effects due to dysbiosis.
Pseudomonas is a genus of Gram-negative bacteria belonging to the family Pseudomonadaceae in the class Gammaproteobacteria.The 348 members of the genus [2] [3] demonstrate a great deal of metabolic diversity and consequently are able to colonize a wide range of niches and hosts.
Pseudomonas can, in rare circumstances, cause community-acquired pneumonias, [39] as well as ventilator-associated pneumonias, being one of the most common agents isolated in several studies. [40] Pyocyanin is a virulence factor of the bacteria and has been known to cause death in C. elegans by oxidative stress .
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Pseudomonas infection refers to a disease caused by one of the species of the genus Pseudomonas. P. aeruginosa is a germ found in the environment and it is an opportunistic human pathogen most commonly infecting immunocompromised patients, such as those with cancer , diabetes , cystic fibrosis , [ 1 ] severe burns, AIDS , [ 2 ] or people who ...
Microscopic image of gram-negative Pseudomonas aeruginosa bacteria (pink-red rods). Gram-negative bacteria are bacteria that, unlike gram-positive bacteria, do not retain the crystal violet stain used in the Gram staining method of bacterial differentiation. [1]
Pseudomonas fluorescens is a common Gram-negative, rod-shaped bacterium. [1] It belongs to the Pseudomonas genus ; 16S rRNA analysis as well as phylogenomic analysis has placed P. fluorescens in the P. fluorescens group within the genus, [ 2 ] [ 3 ] to which it lends its name.