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Urolithins are microflora metabolites of dietary ellagic acid derivatives, such as ellagitannins. [1] They are produced in the gut , and found in the urine in the form of urolithin B glucuronide after absorption of ellagitannins-containing foods, such as pomegranate . [ 2 ]
When synthesized and absorbed in the intestines, urolithin A enters the systemic circulation where it becomes available to tissues throughout the body where it is further subjected to additional chemical transformations (including glucuronidation, methylation, sulfation, or a combination of them) within the enterocytes and hepatocytes. [9]
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The urinary system refers to the structures that produce and transport urine to the point of excretion. In the human urinary system there are two kidneys that are located between the dorsal body wall and parietal peritoneum on both the left and right sides. The formation of urine begins within the functional unit of the kidney, the nephrons.
When I finally delved into Book Three , it soon became obvious that the remainder of the story was far too big to fit in one volume. Having spent so long thinking about the series as a trilogy, it was difficult for me to realize that, in order to be true to my characters and to address all of the plot points and unanswered questions Eragon and ...