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Sertoli–Leydig cell tumour is a testosterone-secreting ovarian tumor and is a member of the sex cord-stromal tumour group [2] of ovarian and testicular cancers. The tumour occurs in early adulthood (not seen in newborn), is rare, comprising less than 1% of testicular tumours. [ 1 ]
A hilar cell tumor is an androgen-producing ovarian tumor that is most commonly found in older women and often leads to the development of male sex characteristics. The tumor tends to occur around the region of the ovary where the blood vessels enter the organ, known as the hilum. This type of tumor tends to be small in size and in most cases ...
An androgen-dependent condition, disease, disorder, or syndrome, is a medical condition that is, in part or full, dependent on, or is sensitive to, the presence of androgenic activity in the body. [ citation needed ]
Androgen-secreting tumors: These are rare tumors that produce androgens and can cause acne in both men and women (though the tumors are more common in women). Deposit Photos Genetics
However, high androgen hormone and insulin levels may contribute to this condition, according to the U.S. Office on Women's Health. If a person's mother has PCOS, that person might have it, too.
Androgen-secreting tumors: Tumors in the adrenal glands or in the ovaries leading to increase levels of androgens. [19] Rapid progression and virilization symptoms. [14] Other less common hormonal causes: Acromegaly: Elevated levels of insulin-like growth factor-1. [18] Hyperthyroidism or hypothyroidism: Elevated or decreased levels of thyroid ...
Antiandrogens are used in the treatment of androgen-dependent skin and hair conditions including acne, seborrhea, hidradenitis suppurativa, hirsutism, and pattern hair loss in women. [12] All of these conditions are dependent on androgens, and for this reason, antiandrogens are effective in treating them. [12]
The majority of Leydig cell tumors are found in males, usually at 5–10 years of age or in middle adulthood (30–60 years). Children typically present with precocious puberty. [citation needed] Due to excess testosterone secreted by the tumour, one-third of female patients present with a recent history of progressive masculinization.