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Ganglionated plexi (GP, also called Ganlionic plexi) comprise the intrinsic cardiac autonomic nervous system composed of autonomic ganglia of the heart atrium and ventricles. [1] Cholinergic neurons throughout the GPs project to all areas of the heart, [ 2 ] The GP are embedded in the epicardial fat pads, consisting of only a few neurons or as ...
The division of coagulation in two pathways is arbitrary, originating from laboratory tests in which clotting times were measured either after the clotting was initiated by glass, the intrinsic pathway; or clotting was initiated by thromboplastin (a mix of tissue factor and phospholipids), the extrinsic pathway. [32]
An increase in sympathetic stimulation to the heart increases contractility and heart rate. An increase in contractility tends to increase stroke volume and thus a secondary increase in preload. An increase in preload results in an increased force of contraction by Starling's law of the heart; this does not require a change in contractility.
The extrinsic pathway of apoptosis refers to cell death induced by external factors that activate the death-inducing signaling complex. The extrinsic pathway of blood coagulation is also known as the tissue factor pathway and refers to a cascade of enzymatic reactions resulting in blood clotting and is done with the addition of injured tissue ...
A slow heart rate of 60 or less beats per minute is defined as bradycardia. A fast heart rate of more than 100 beats per minute is defined as tachycardia. An arrhythmia is defined as one that is not physiological such as the lowered heart rate that a trained athlete may naturally have developed; the resting heart rates may be less than 60 bpm.
Blood coagulation pathways in vivo showing the central role played by thrombin. Factor Xa is the activated form of the coagulation factor X, also known as thrombokinase. Factor X is an enzyme, a serine endopeptidase, which plays a key role at several stages of the coagulation system. Factor X is synthesized in the liver.
The prothrombin time (PT) – along with its derived measures of prothrombin ratio (PR) and international normalized ratio (INR) – is an assay for evaluating the extrinsic pathway and common pathway of coagulation. This blood test is also called protime INR and PT/INR.
Bachmann's bundle receives its blood supply from the sinoatrial nodal artery (right, left or both). [4]Besides Bachmann's bundle, the other three conduction tracts that constitute the atrial conduction system are known as the anterior, middle, and posterior tracts, which run from the sinoatrial node to the atrioventricular node, converging in the region near the coronary sinus.