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Bacteriophage genomes can be highly mosaic, i.e. the genome of many phage species appear to be composed of numerous individual modules. These modules may be found in other phage species in different arrangements. Mycobacteriophages, bacteriophages with mycobacterial hosts, have provided excellent examples of this mosaicism.
Although bacteriophages cannot infect human cells, they are found in abundance in the human virome. [7] Phageome research in humans has largely focused on the gut, however it is also being investigated in other areas like the skin, [ 8 ] blood, [ 9 ] and mouth. [ 10 ]
Bacteriophages occur in over 1100 bacterial or archaeal genera. [3] Over 6300 bacteriophages have been examined in the electron microscope since 1959. Of these, more than 96 percent have tails. Of the tailed phages, about 57 percent have long, noncontractile tails ("Siphoviridae"). Tailed phages appear to be monophyletic and are the oldest ...
This causes pharyngitis and 'pseudomembrane' in the throat. The strains that are toxigenic are ones which have been infected with a bacteriophage. [11] [12] The diphtheria toxin gene is encoded by the bacteriophage found in toxigenic strains, integrated into the bacterial chromosome. [13] The diphtheria toxin repressor is mainly controlled by iron.
The prokaryotic cell is shown with its DNA, in green. 2. The bacteriophage attaches and releases its DNA, shown in red, into the prokaryotic cell. 3. The phage DNA then moves through the cell to the host's DNA. 4. The phage DNA integrates itself into the host cell's DNA, creating prophage. 5. The prophage then remains dormant until the host ...
In a 1945 study by Demerec and Fano, [4] T7 was used to describe one of the seven phage types (T1 to T7) that grow lytically on Escherichia coli. [5] Although all seven phages were numbered arbitrarily, phages with odd numbers, or T-odd phages, were later discovered to share morphological and biochemical features that distinguish them from T-even phages. [6]
In order for the T-even phage to infect its host and begin its life cycle it must enter the first process of infection, adsorption of the phage to the bacterial cell. Adsorption is a value characteristic of phage-host pair and the adsorption of the phage on host cell surface is illustrated as a 2-stage process: reversible and irreversible.
A bacteriophage is a type of virus that infects bacteria. Bacteriophage are likely the most numerous "organisms" on Earth [1] [2] The main article for this category is Bacteriophage .