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It decreases LDL by 15–30% and raises HDL by 3–5%, with little effect on triglycerides, but can cause a slight increase. Bile acid sequestrants may cause gastrointestinal problems and may also reduce the absorption of other drugs and vitamins from the gut. Ezetimibe is a selective inhibitor of dietary cholesterol absorption.
At the end of the third year, 54% of women had been treated with cholesterol-lowering medications compared with 74% of men. Five percent of women were treated with statins compared to 8% of men.
Cholesterolemia and mortality for men and women <50 years and >60 years. With the increased use of medication to suppress cholesterol, some have expressed concern that lowering cholesterol levels excessively will itself cause disease. [citation needed]
In women, testosterone is involved in the development and maintenance of lean muscle mass. It also influences how fat is distributed in the body. Low testosterone levels may lead to more fat ...
They inhibit release of thyroid hormones by the thyroid gland.The most studied drug in this class is lithium, which inhibits thyroid hormone secretion by inhibiting iodotyrosine coupling, thyroidal iodide uptake, and alteration in structure of thyroglobulin, [10] a protein which acts as a substrate for the synthesis of thyroid hormones and storage of inactive forms of T3, T4 and iodine within ...
Both medications target people born with a genetic predisposition to high cholesterol. While drugs like statins , as well as diet and exercise, can help these individuals manage cholesterol, they ...
Older people should be started on lower doses of liothyronine. [12] Plasma T 3 concentrations in this population are decreased by 25% to 40%. [ 10 ] TSH must be routinely monitored since there is a risk of coronary artery disease , hyperthyroidism and excessive bone loss from inadequate or abnormal thyroid replacement.
Fasting in healthy, euthyroid people causes reduced T3 and elevated rT3, although TSH is usually unchanged. [3] [5] [10] Even moderate weight loss can lower T3. [2] This may be primarily via reduced levels of leptin (the satisfaction hormone). Low leptin levels can downregulate hypothalamic TRH neurons and cause a reduction in TSH.