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Voriconazole, sold under the brand name Vfend among others, is an antifungal medication used to treat a number of fungal infections. [5] This includes aspergillosis , candidiasis , coccidioidomycosis , histoplasmosis , penicilliosis , and infections by Scedosporium or Fusarium . [ 5 ]
Posaconazole, sold under the brand name Noxafil among others, is a triazole antifungal medication. [ 7 ] [ 8 ] It was approved for medical use in the European Union in October 2005, [ 6 ] and in the United States in September 2006.
Allergic bronchopulmonary aspergillosis (ABPA) is diagnosed by establishing an immune sensitization to aspergillosis, which can be done by measuring total eosinophils, total immunoglobulin E (IgE) and aspergillus specific IgE and IgG levels. Elevations of these markers, combined with clinical and radiologic findings suggesting infection are ...
Itraconazole has a broader spectrum of activity than fluconazole (but not as broad as voriconazole or posaconazole). In particular, it is active against Aspergillus, which fluconazole is not. The mechanism of action of itraconazole is the same as the other azole antifungals: it inhibits the fungal-mediated synthesis of ergosterol .
An antifungal medication, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis (thrush), serious systemic infections such as cryptococcal meningitis, and others.
Treatment is generally performed using antifungal medicines, usually in the form of a cream or by mouth or injection, depending on the specific infection and its extent. [15] Some require surgically cutting out infected tissue. [3] Fungal infections have a world-wide distribution and are common, affecting more than one billion people every year ...
Other oral triazoles, such as itraconazole and voriconazole can be other options. [3] Amphotericin B can be used in nonresponsive cases, but should not be used routinely due to its serious side effects. [3] Posaconazole is effective in severe and refractory esophageal candidiasis. [3]
Itraconazole is a relatively well-tolerated drug (although not as well tolerated as fluconazole or voriconazole) and the range of adverse effects it produces is similar to the other azole antifungals: [22] elevated alanine aminotransferase levels are found in 4% of people taking itraconazole
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3579 S High St, Columbus, OH · Directions · (614) 409-0683