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  2. Evolutionary mismatch - Wikipedia

    en.wikipedia.org/wiki/Evolutionary_mismatch

    Evolutionary mismatch (also "mismatch theory" or "evolutionary trap") is the evolutionary biology concept that a previously advantageous trait may become maladaptive due to change in the environment, especially when change is rapid. It is said this can take place in humans as well as other animals.

  3. DNA mismatch repair - Wikipedia

    en.wikipedia.org/wiki/DNA_mismatch_repair

    Because the distance between the nick created by MutH and the mismatch can average ~600 bp, if there is not another UvrD loaded the unwound section is then free to re-anneal to its complementary strand, forcing the process to start over. However, when assisted by MutL, the rate of UvrD loading is greatly increased. While the processivity (and ...

  4. Genotype–phenotype distinction - Wikipedia

    en.wikipedia.org/wiki/Genotype–phenotype...

    T 1 represents the genetic and epigenetic laws, the aspects of functional biology, or development, that transform a genotype into phenotype. This is the " genotype–phenotype map ". T 2 is the transformation due to natural selection, T 3 are epigenetic relations that predict genotypes based on the selected phenotypes and finally T 4 the rules ...

  5. Genetic transformation - Wikipedia

    en.wikipedia.org/wiki/Genetic_transformation

    Exactly how the T-DNA is integrated into the host plant genomic DNA is an active area of plant biology research. Assuming that a selection marker (such as an antibiotic resistance gene) was included in the T-DNA, the transformed plant tissue can be cultured on selective media to produce shoots.

  6. Overlapping gene - Wikipedia

    en.wikipedia.org/wiki/Overlapping_gene

    The current definition of an overlapping gene varies significantly between eukaryotes, prokaryotes, and viruses. [2] In prokaryotes and viruses overlap must be between coding sequences but not mRNA transcripts, and is defined when these coding sequences share a nucleotide on either the same or opposite strands.

  7. Neutral theory of molecular evolution - Wikipedia

    en.wikipedia.org/wiki/Neutral_theory_of...

    CNE, which does not invoke adaptationist mechanisms for the origins of more complex systems (which involve more parts and interactions contributing to the whole), has seen application in the understanding of the evolutionary origins of the spliceosomal eukaryotic complex, RNA editing, additional ribosomal proteins beyond the core, the emergence ...

  8. Genetic viability - Wikipedia

    en.wikipedia.org/wiki/Genetic_viability

    [1] [2] The term is generally used to mean the chance or ability of a population to avoid the problems of inbreeding. [1] Less commonly genetic viability can also be used in respect to a single cell or on an individual level. [1] Inbreeding depletes heterozygosity of the genome, meaning there is a greater chance of identical alleles at a locus. [1]

  9. Genetic correlation - Wikipedia

    en.wikipedia.org/wiki/Genetic_correlation

    Genetic correlations are not the same as heritability, as it is about the overlap between the two sets of influences and not their absolute magnitude; two traits could be both highly heritable but not be genetically correlated or have small heritabilities and be completely correlated (as long as the heritabilities are non-zero).