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A biosafety level (BSL), or pathogen/protection level, is a set of biocontainment precautions required to isolate dangerous biological agents in an enclosed laboratory facility. The levels of containment range from the lowest biosafety level 1 (BSL-1) to the highest at level 4 (BSL-4).
A biosafety cabinet (BSC)—also called a biological safety cabinet or microbiological safety cabinet—is an enclosed, ventilated laboratory workspace for safely working with materials contaminated with (or potentially contaminated with) pathogens requiring a defined biosafety level.
The levels of containment range from the lowest biosafety level 1 (BSL-1) to the highest at level 4 (BSL-4). In the United States, the Centers for Disease Control and Prevention (CDC) have specified these levels. [8] In the European Union, the same biosafety levels are defined in a directive. [9]
In the late 1970s, ILC Dover, LP, developed a special garment, the Demilitarization Protective Ensemble (DPE), to fulfill the U.S. Army's need for an off-the-shelf, positive pressure, totally encapsulating suit for use by maintenance personnel at a chemical weapons site.
The United States Centers for Disease Control and Prevention (CDC) categorizes various diseases in levels of biohazard, Level 1 being minimum risk and Level 4 being extreme risk. Laboratories and other facilities are categorized as BSL (Biosafety Level) 1–4 or as P1 through P4 for short (Pathogen or Protection Level). [citation needed]
Biosafety is the prevention of large-scale loss of biological integrity, focusing both on ecology and human health. [1] These prevention mechanisms include the conduction of regular reviews of biosafety in laboratory settings, as well as strict guidelines to follow. Biosafety is used to protect from harmful incidents.
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NEIDL is one of only 13 operational or planned biosafety level 4 (BSL-4) laboratories in the United States. NEIDL's current director is Nancy Sullivan, ScD . She previously served as the chief of the Biosecurity Research Section at the Vaccine Research Center of the National Institute of Allergy and Infectious Diseases (NIAID) in the National ...