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PCBs collect in body fat and milk fat. [56] PCBs biomagnify up the food web and are present in fish and overflow of contaminated aquifers. [57] Human infants are exposed to PCBs through breast milk or by intrauterine exposure through transplacental transfer of PCBs [56] and are at the top of the food chain. [58]: 249ff
The toxicological interactions of PCBs are affected by the number and position of the chlorine atoms, without ortho substitution are referred as coplanar and all others as non-coplanar. [5] Non-coplanar PCBs may cause neurotoxicity by interfering with intracellular signal transduction dependent on calcium. [7]
Human exposure to dioxins and DLCs is a cause for public and regulatory concern. [5] Health concerns include endocrine, developmental, immune and carcinogenic effects. [ 12 ] The route of exposure is primarily through the ingestion of animal products such as meat, dairy, fish, and human breast milk. [ 12 ]
Polychlorinated biphenyls (PCBs), derived from biphenyl, of which 12 are "dioxin-like". Under certain conditions PCBs may form dibenzofurans through partial oxidation. Polybrominated analogs of the above classes may have similar effects. "Dioxin" can also refer to 1,4-dioxin or p-dioxin, the basic chemical unit of the more complex dioxins. This ...
Nov. 13, 2023: An additional lab, SGS Galson, received samples of the air in Poe Hall. The company reported the results to NC State on Nov. 14. The results did not appear to indicate ...
Exposure to high levels of dioxins in humans causes a severe form of persistent acne, known as chloracne. [34] High occupational or accidental levels of exposures to dioxins have been shown by epidemiological studies to lead to an increased risk of tumors at all sites. [35] Other effects in humans (at high dose levels) may include:
PCB contamination in humans may come from drinking the contaminated water, absorption through the skin, eating contaminated aquatic life, and/or inhaling volatilized PCBs. PCB contamination is especially dangerous for pregnant and nursing women. The contamination can reach the fetus and potentially cause birth defects.
Xenoestrogens are a type of xenohormone that imitates estrogen.They can be either synthetic or natural chemical compounds.Synthetic xenoestrogens include some widely used industrial compounds, such as PCBs, BPA, and phthalates, which have estrogenic effects on a living organism even though they differ chemically from the estrogenic substances produced internally by the endocrine system of any ...