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A box of Lorazepam Orion (Lorazepam) tablets. Lorazepam, sold under the brand name Ativan among others, is a benzodiazepine medication. [14] It is used to treat anxiety (including anxiety disorders), trouble sleeping, severe agitation, active seizures including status epilepticus, alcohol withdrawal, and chemotherapy-induced nausea and vomiting. [14]
Benzodiazepines require special precaution if used in the elderly, during pregnancy, in children, alcohol or drug-dependent individuals and individuals with comorbid psychiatric disorders. [17] Loprazolam, similar to other benzodiazepines and nonbenzodiazepine hypnotic drugs causes impairments in body balance and standing steadiness in ...
In terms of the mechanism of action of benzodiazepines, their similarities are too great to separate them into individual categories such as anxiolytic or hypnotic. For example, a hypnotic administered in low doses produces anxiety-relieving effects, whereas a benzodiazepine marketed as an anti-anxiety drug at higher doses induces sleep. [175]
4.1 Mechanism of action. 4.2 Pharmacokinetics. ... Particular care should be taken in pregnant or elderly people, ... or lorazepam. Factors that ...
Lorazepam (Ativan) is said to be very good as an adjunct treatment for nausea along with first line medications such as Compazine. [citation needed] Anticholinergics. Hyoscine (also known as scopolamine) Atropine; Steroids. Dexamethasone (Decadron) is given in low dose at the onset of a general anesthetic as an effective antiemetic.
The mechanism of action of mood stabilizers is not well understood. Common non-antipsychotic mood stabilizers include: Lithium (Lithobid, Eskalith), the oldest mood stabilizer; Anticonvulsants Carbamazepine (Tegretol) and the related compound oxcarbazepine (Trileptal) Valproic acid, and salts (Depakene, Depakote) Lamotrigine (Lamictal)
The authors also warned of the similarities in pharmacology and mechanism of action of the newer nonbenzodiazepine Z drugs. [136] The elimination half-life of diazepam and chlordiazepoxide, as well as other long half-life benzodiazepines, is twice as long in the elderly compared to younger individuals. Many doctors do not adjust benzodiazepine ...
Use of anticonvulsant medications should be carefully monitored during use in pregnancy. [94] For example, since the first trimester is the most susceptible period for fetal development, planning a routine antiepileptic drug dose that is safer for the first trimester could be beneficial to prevent pregnancy complications. [95]