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For example, phosgene was initially blamed for the Bhopal disaster, but investigations proved methyl isocyanate to be responsible for the numerous poisonings and fatalities. Recent major incidents happened in January 2010 and May 2016. An accidental release of phosgene gas at a DuPont facility in West Virginia killed one employee in 2010. [41]
Highly Toxic: a gas that has a LC 50 in air of 200 ppm or less. [2] NFPA 704: Materials that, under emergency conditions, can cause serious or permanent injury are given a Health Hazard rating of 3. Their acute inhalation toxicity corresponds to those vapors or gases having LC 50 values greater than 1,000 ppm but less than or equal to 3,000 ppm ...
In recent years, researchers have successfully developed experimental brain–computer interfaces or neuroprostheses that stimulate phosphenes to restore vision to people blinded through accidents. Notable successes include the human experiments by William H. Dobelle [13] and Mark Humayun and animal research by Dick Normann.
In low concentrations, phosgene’s odor resembles freshly cut hay or grass. Because of this, the gas may not be noticed and symptoms may appear slowly. Phosgene directly reacts with amine, sulfhydryl, and alcohol groups, adversely affecting cell macromolecules and metabolism. The direct toxicity to the cells leads to an increase in capillary ...
Traces of a toxic, colorless gas were found at the headquarters of Sweden’s security agency where a suspected gas leak last week forced authorities to evacuate some 500 people from the facility ...
Phosgene is the most dangerous commonly used pulmonary agent (although disulfur decafluoride and perfluoroisobutene are both even more dangerous, with respectively 4 and 10 times the lethality of phosgene, neither is widely used). It is a colorless gas under ordinary conditions.
In the subsequent autopsy, Bartholow noted that some brain damage had occurred due to the electrodes but that she had died due to the cancer. Bartholow was criticized by fellow physicians and the American Medical Association formally condemned his experiments as he had caused direct harm to the patient, not in an attempt to treat her, but solely to gain knowledge.
It is likely that such effects have an effect on the blood supply to the brain. That such an effect might well lead to damage to the brain seems likely. Therefore it is regarded that the association between exposure to air pollutants and effects on cognitive decline and dementia as likely to be causal with respect to this mechanism. [65]