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Glycosuria is the excretion of glucose into the urine. Ordinarily, urine contains no glucose because the kidneys are able to reabsorb all of the filtered glucose from the tubular fluid back into the bloodstream. Glycosuria is nearly always caused by an elevated blood sugar level, most commonly due to untreated diabetes.
According to the American Diabetes Association, the fasting blood glucose target range for diabetics, should be 3.9 - 7.2 mmol/L (70 - 130 mg/dL) and less than 10 mmol/L (180 mg/dL) two hours after meals (as measured by a blood glucose monitor). [6][7][9] Normal value ranges may vary slightly between laboratories.
Renal glucose reabsorption is the part of kidney (renal) physiology that deals with the retrieval of filtered glucose, preventing it from disappearing from the body through the urine. If glucose is not reabsorbed by the kidney, it appears in the urine, in a condition known as glycosuria. This is associated with diabetes mellitus.
In practice, the transport maximum is not all-or-nothing. As the concentration approaches the transport maximum, some of the channels are overwhelmed before others are. For example, with glucose, some sugar appears in the urine at levels much lower than 300 mg/dL. [2]
The presence of glucose in the urine is known as glycosuria. In people with normal blood sugar levels, the amount of glucose in the urine should be negligible as it is reabsorbed by the renal tubules. [72] High blood sugar levels (hyperglycemia) cause excess glucose to
A urine test strip or dipstick is a basic diagnostic tool used to determine pathological changes in a patient's urine in standard urinalysis. [1] A standard urine test strip may comprise up to 10 different chemical pads or reagents which react (change color) when immersed in, and then removed from, a urine sample.
Benedict's quantitative reagent contains potassium thiocyanate and is used to quantitatively determine the concentration of reducing sugars. [2] This solution forms a copper thiocyanate precipitate which is white and can be used in titration. The titration should be repeated with 1% glucose solution instead of the sample for calibration.
The glucose tolerance test was first described in 1923 by Jerome W. Conn. [4]The test was based on the previous work in 1913 by A. T. B. Jacobson in determining that carbohydrate ingestion results in blood glucose fluctuations, [5] and the premise (named the Staub-Traugott Phenomenon after its first observers H. Staub in 1921 and K. Traugott in 1922) that a normal patient fed glucose will ...
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