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  2. Gabapentin - Wikipedia

    en.wikipedia.org/wiki/Gabapentin

    Gabapentin is recommended for use in focal seizures and neuropathic pain. [7] [10] Gabapentin is prescribed off-label in the US and the UK, [22] [23] for example, for the treatment of non-neuropathic pain, [22] anxiety disorders, sleep problems and bipolar disorder. [24] In recent years, gabapentin has seen increased use, particularly in the ...

  3. Gabapentinoid - Wikipedia

    en.wikipedia.org/wiki/Gabapentinoid

    The oral bioavailability of gabapentin enacarbil (as gabapentin) is greater than or equal to 68%, across all doses assessed (up to 2,800 mg), with a mean of approximately 75%. [ 25 ] [ 1 ] In contrast to the other gabapentinoids, the pharmacokinetics of phenibut have been little-studied, and its oral bioavailability is unknown. [ 28 ]

  4. Pregabalin - Wikipedia

    en.wikipedia.org/wiki/Pregabalin

    Pregabalin, sold under the brand name Lyrica among others, is an anticonvulsant, analgesic, and anxiolytic amino acid medication used to treat epilepsy, neuropathic pain, fibromyalgia, restless legs syndrome, opioid withdrawal, and generalized anxiety disorder (GAD).

  5. Gabapentin enacarbil - Wikipedia

    en.wikipedia.org/wiki/Gabapentin_enacarbil

    Gabapentin enacarbil (Horizant (ER) (U.S. Tooltip United States), Regnite (in Japan)) is an anticonvulsant and analgesic drug of the gabapentinoid class, and a prodrug to gabapentin. [1] It was designed for increased oral bioavailability over gabapentin, [ 2 ] [ 3 ] and human trials showed it to produce extended release of gabapentin with ...

  6. ‘My Low Back Pain Turned Out To Be A Rare Inflammatory ...

    www.aol.com/low-back-pain-turned-rare-120000344.html

    At the recommendation of my doctor, I started taking Lyrica, a medication that helps treat nerve pain. Anytime I stopped taking the medication, I felt a burning pain in my thighs. In 2022, the ...

  7. Can Gabapentin Really Cause ED? - AOL

    www.aol.com/lifestyle/gabapentin-really-cause-ed...

    Gabapentin is also associated with other intimate side effects, like difficulty reaching orgasm, although the science on this link isn’t totally clear. ED from gabapentin isn’t permanent.

  8. Voltage-gated calcium channel - Wikipedia

    en.wikipedia.org/wiki/Voltage-gated_calcium_channel

    This drug class includes two anticonvulsant drugs, gabapentin (Neurontin) and pregabalin (Lyrica), that also find use in treating chronic neuropathic pain. The α 2 δ subunit is also a binding site of the central depressant and anxiolytic phenibut , in addition to actions at other targets.

  9. Umbrella review - Wikipedia

    en.wikipedia.org/wiki/Umbrella_review

    In medical research, an umbrella review is a review of systematic reviews or meta-analyses. [1] [2] [3] They may also be called overviews of reviews, reviews of reviews, summaries of systematic reviews, or syntheses of reviews. [1] Umbrella reviews are among the highest levels of evidence currently available in medicine. [2]

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