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  2. Fentanyl - National Institute on Drug Abuse (NIDA)

    nida.nih.gov/research-topics/fentanyl

    Fentanyl is a powerful synthetic (lab-made) opioid that is FDA-approved to treat severe pain related to surgery or complex pain conditions. 1,2 Over the past decade, fentanyl that is made and distributed illegally (sometimes called “illicitly manufactured fentanyl”) and other illegally made synthetic opioids have been increasingly found in the drug supply. 3,4 During this time, fentanyl ...

  3. Naloxone DrugFacts | National Institute on Drug Abuse (NIDA)

    nida.nih.gov/publications/drugfacts/naloxone

    When naloxone was first approved to reverse opioid overdoses, its brand name was “Narcan.” There are now other formulations and brand names for naloxone, but many people continue to call all of these products “Narcan.” However, the proper generic name is “naloxone.”

  4. Opioids | National Institute on Drug Abuse (NIDA)

    nida.nih.gov/research-topics/opioids

    Opioids are a class of drugs that include synthetic opioids such as fentanyl; pain relievers available legally by prescription, such as oxycodone (OxyContin®), hydrocodone (Vicodin®), codeine, morphine; the illegal drug heroin; and many others.

  5. Xylazine | National Institute on Drug Abuse (NIDA)

    nida.nih.gov/research-topics/xylazine

    When people take xylazine with fentanyl, it is not clear if xylazine increases the risk of fatal overdose. However, extreme sedation from xylazine can cause people to stop breathing. Most overdose deaths linked to both xylazine and fentanyl also involved other substances, including cocaine, heroin, benzodiazepines, alcohol, gabapentin, and ...

  6. What do drug tests really tell us? | National Institute on Drug...

    nida.nih.gov/news-events/nida-asks/what-do-drug-tests-really-tell-us

    Three weeks later, the program did a repeat urine drug test that was again positive for fentanyl. Her doctor ordered a much more sensitive and specific type of confirmatory testing. That was also positive, so there were concerns that she had returned to use. However, the patient adamantly denied using fentanyl since entering treatment.

  7. Overdose Reversal Medications | National Institute on Drug Abuse

    nida.nih.gov/research-topics/overdose-reversal-medications

    NIDA is advancing the science on emergency medications like naloxone, which can save a life during an opioid overdose. Overdose reversal medications are safe and effective life-saving tools that can be given to someone experiencing a drug overdose. As a harm reduction tool, overdose reversal medications play a critical role in a science-based approach to the drug overdose crisis.

  8. Commonly Used Drugs Charts | National Institute on Drug Abuse

    nida.nih.gov/research-topics/commonly-used-drugs-charts

    A dissociative drug developed as an intravenous anesthetic that has been discontinued due to serious adverse effects. Dissociative drugs are hallucinogens that cause the user to feel detached from reality. PCP is an abbreviation of the scientific name, phencyclidine. For more information, see Psychedelic and Dissociative Drugs.

  9. Prevent Overdose: Empowering Youth to Save Lives

    nida.nih.gov/sites/default/files/NDAFW-2024-Preventing-an-Overdose...

    Facts on Fentanyl Fentanyl is a powerful, lab-made opioid. •It is often added to drugs like cocaine, meth, and illicit pills that dealers manufacture to look identical to real prescription pills. Much stronger than other opioids like heroin It has no taste or smell. It’s hard to detect if mixed with drugs.

  10. Medications for Opioid Overdose, Withdrawal, & Addiction

    nida.nih.gov/research-topics/opioids/medications-opioid-overdose-withdrawal...

    Explore the different types of medications prescribed for opioid overdose, withdrawal, and addiction. Medications for overdose of opioids, withdrawal, and addiction are safe, effective, and save lives. This Medications for Opioid Use Disorder (MOUD) Infographic helps present basic information on common medications and formulations available to consumers.

  11. To address the fentanyl crisis, greater access to methadone is...

    nida.nih.gov/about-nida/noras-blog/2024/07/to-address-the-fentanyl-crisis...

    Growing evidence suggests that methadone is as safe and effective as buprenorphine for patients who use fentanyl. In a 2020 naturalistic follow-up study, 53% of patients admitted to methadone treatment who tested positive for fentanyl at intake were still in treatment a year later, compared to 47% for patients who tested negative.