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Z21 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. Short description: Asymptomatic human immunodeficiency virus infection status; The 2025 edition of ICD-10-CM Z21 became effective on October 1, 2024.
Code Z21 is used for patients who are asymptomatic, meaning they are HIV positive but have never had an HIV-related condition. Once that patient experiences an HIV-related condition, the Z21 code is no longer appropriate.
Z21 is a billable diagnosis code used to specify a medical diagnosis of asymptomatic human immunodeficiency virus [hiv] infection status. The code is valid during the current fiscal year for the submission of HIPAA-covered transactions from October 01, 2024 through September 30, 2025.
Apply Z21 Asymptomatic human immunodeficiency virus [HIV] infection status when the patient is HIV positive and does not have any documented symptoms of an HIV-related illness. Do not use this code if the term AIDS is used.
Z21 is a valid billable ICD-10 diagnosis code for Asymptomatic human immunodeficiency virus [HIV] infection status. It is found in the 2025 version of the ICD-10 Clinical Modification (CM) and can be used in all HIPAA-covered transactions from Oct 01, 2024 - Sep 30, 2025.
Following ICD-10 guidelines, if a patient has or has had an HIV related condition, use B20 AIDS. If the patient has a positive HIV status, without symptoms or related conditions, use Z21. See the excerpts from the ICD-10-CM General Guidelines, below.
Get crucial instructions for accurate ICD-10-CM Z21 coding with all applicable Excludes 1 and Excludes 2 notes from the section level conveniently shown with each code.
Following ICD-10 guidelines, a patient with HIV status without symptoms is coded with Z21, positive HIV status. Some doctors and non-physician practitioners would prefer to use B20.
Z21 is a billable ICD code used to specify a diagnosis of asymptomatic human immunodeficiency virus [HIV] infection status. A 'billable code' is detailed enough to be used to specify a medical diagnosis.
Browse all the diagnosis codes used for asymptomatic human immunodeficiency virus [hiv] infection status (z21). For easy navigation, the diagnosis codes are sorted in alphabetical order and grouped by sections. Each section is clearly marked with its description, and the corresponding three-digit code range.