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Leukocyte esterase (LE) is an esterase (a type of enzyme) produced by leukocytes (white blood cells). A leukocyte esterase test (LE test) is a urine test for the presence of white blood cells and other abnormalities associated with infection. White blood cells in the urine can indicate a urinary tract infection (UTI). Positive test results may ...
Procedures in urinalysis. Left: A urine test strip is immersed into the sample. Top right: Urine is about to be examined under a phase-contrast microscope using a Neubauer counting chamber. Bottom right: Phase-contrast microscopic image showing many white blood cells in the urine .
Automatic analysis of urine test strips using automated urine test strip analysers is a well-established practice in modern-day urinalysis. They can measure calcium , blood, glucose, bilirubin, urobilinogen, ketones, leukocytes, creatinine , microalbumin , pH, ascorbic acid and protein.
Pyuria is the condition of urine containing white blood cells or pus. Defined as the presence of 6-10 or more neutrophils per high power field of unspun, voided mid-stream urine, it can be a sign of a bacterial urinary tract infection. Pyuria may be present in people with sepsis, or in older people with pneumonia.
In complicated or questionable cases, it may be useful to confirm the diagnosis via urinalysis, looking for the presence of urinary nitrites, white blood cells (leukocytes), or leukocyte esterase. [54] Another test, urine microscopy, looks for the presence of red blood cells, white blood cells, or bacteria.
Reference ranges for urine tests are described below: Measurement Lower limit Upper limit ... White blood cells (WBCs) 0 [2] 2 [2] pH: 5 [2] 7 [2] (unitless) Protein ...
The leukocyte esterase test indirectly detects the presence of leukocytes (white blood cells) in urine which can be associated with a urinary tract infection. In the elderly, the leukocyte esterase test is often positive even in the absence of an infection.
Glitter cells (also called Sternheimer-Malbin positive cells) are polymorphonuclear leukocyte neutrophils with granules that show a Brownian movement and that are found in the urine, most commonly associated with urinary tract infections or pyelonephritis and especially prevalent under conditions of hypotonic urine (samples with specific gravity less than 1.01). [1]