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Hyperammonemia, or high ammonia levels, is a metabolic disturbance characterised by an excess of ammonia in the blood. Severe hyperammonemia is a dangerous condition that may lead to brain injury and death. It may be primary or secondary. Ammonia is a substance that contains nitrogen. It is a product of the catabolism of protein.
Although it has been defined as an extension of pneumoconiosis, there is no scientific evidence for a similar disease related to volcanic silica particle exposures. [8] Subsequently, the word was used in Frank Scully's puzzle book Bedside Manna, after which time, members of the N.P.L. campaigned to include the word in major dictionaries. [9] [10]
Ammonia is generally used in household cleaning products, as well as on farms and in some industrial and commercial locations, and this makes it easy for accidental or deliberate exposure to occur. [15] [16] [17] Ammonia interacts with moist surfaces to form ammonium hydroxide, which causes necrosis of tissues. Exposure to high concentrations ...
The diagnosis of hepatic encephalopathy is a clinical one, once other causes for confusion or coma have been excluded; no test fully diagnoses or excludes it. Serum ammonia levels are elevated in 90% of people, but not all hyperammonaemia (high ammonia levels in the blood) is associated with encephalopathy.
Ammonia is an inorganic chemical compound of nitrogen and hydrogen with the ... as well as the neurological disease common in people with urea cycle defects and ...
Protein toxicity is the effect of the buildup of protein metabolic waste compounds, like urea, uric acid, ammonia, and creatinine.Protein toxicity has many causes, including urea cycle disorders, genetic mutations, excessive protein intake, and insufficient kidney function, such as chronic kidney disease and acute kidney injury.
Argininemia is an autosomal recessive urea cycle disorder where a deficiency of the enzyme arginase causes a buildup of arginine and ammonia in the blood.Ammonia, which is formed when proteins are broken down in the body, is toxic if levels become too high; the nervous system is especially sensitive to the effects of excess ammonia.
The disease may be classified by where it was acquired, such as community- or hospital-acquired or healthcare-associated pneumonia. [ 18 ] Risk factors for pneumonia include cystic fibrosis , chronic obstructive pulmonary disease (COPD), sickle cell disease , asthma , diabetes , heart failure , a history of smoking, a poor ability to cough ...