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  2. Fibrin degradation product - Wikipedia

    en.wikipedia.org/wiki/Fibrin_degradation_product

    When the clot and fibrin net dissolve, fragments of protein are released into the body. These fragments are fibrin degradation products or FDPs. If your body is unable to dissolve a clot, you may have abnormal levels of FDPs. The most notable subtype of fibrin degradation products is D-dimer. The levels of these FDPs rise after any thrombotic ...

  3. Cytokine release syndrome - Wikipedia

    en.wikipedia.org/wiki/Cytokine_release_syndrome

    Lab tests and clinical monitoring show low blood oxygen, widened pulse pressure, increased cardiac output (early), potentially diminished cardiac output (late), high levels of nitrogen compounds in the blood, elevated D-dimer, elevated transaminases, factor I deficiency and excessive bleeding, higher-than-normal level of bilirubin. [5] [8]

  4. Pulmonary drug delivery - Wikipedia

    en.wikipedia.org/wiki/Pulmonary_drug_delivery

    Pulmonary drug delivery is a route of administration in which patients use an inhaler to inhale their medications and drugs are absorbed into the bloodstream via the lung mucous membrane. This technique is most commonly used in the treatment of lung diseases, for example, asthma and chronic obstructive pulmonary disease (COPD) .

  5. D-dimer - Wikipedia

    en.wikipedia.org/wiki/D-dimer

    D-dimer (or D dimer) is a dimer that is a fibrin degradation product (FDP), a small protein fragment present in the blood after a blood clot is degraded by fibrinolysis. It is so named because it contains two D fragments of the fibrin protein joined by a cross-link , hence forming a protein dimer .

  6. Endothelial dysfunction - Wikipedia

    en.wikipedia.org/wiki/Endothelial_dysfunction

    Treatment of hypertension and hypercholesterolemia may improve endothelial function in people taking statins (HMGCoA-reductase inhibitor), and renin angiotensin system inhibitors, such as ACE inhibitors and angiotensin II receptor antagonists. [28] [29] Calcium channel blockers and selective beta 1 antagonists may also improve endothelial ...

  7. Bronchial thermoplasty - Wikipedia

    en.wikipedia.org/wiki/Bronchial_Thermoplasty

    Bronchial thermoplasty [1] is a treatment for severe asthma approved by the FDA in 2010 involving the delivery of controlled, therapeutic radiofrequency energy to the airway wall, thus heating the tissue and reducing the amount of smooth muscle present in the airway wall.

  8. Pathophysiology of asthma - Wikipedia

    en.wikipedia.org/wiki/Pathophysiology_of_asthma

    However, asthma is rarely the only symptom, and not all people with food or other allergies have asthma [17] Sulfite sensitivity Asthma can occur in reaction to ingestion or inhalation of sulfites, which are added to foods and wine as preservatives. [18] Salicylate sensitivity Salicylates can trigger asthma in sensitive individuals. Salicylates ...

  9. Discovery and development of beta2 agonists - Wikipedia

    en.wikipedia.org/wiki/Discovery_and_development...

    They are both inhaled and given by aerosol delivery devices. [5] [6] Long-lasting β 2-agonists are often given in a combination with corticosteroids to treat asthma. Short-acting β 2-agonists are used to treat exercise-induced asthma, [7] and for asthma patients to get a quick relief of symptoms. They are taken 10–15 minutes before exercise.