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  2. Omega-3-acid ethyl esters - Wikipedia

    en.wikipedia.org/wiki/Omega-3-acid_ethyl_esters

    Intake of large doses (2.0 to 4.0 g/day) of long-chain omega3 fatty acids as prescription drugs or dietary supplements are generally required to achieve significant (> 15%) lowering of triglycerides, and at those doses, the effects can be significant (from 20% to 35% and even up to 45% in individuals with levels greater than 500 mg/dL).

  3. Ethyl eicosapentaenoic acid - Wikipedia

    en.wikipedia.org/wiki/Ethyl_eicosapentaenoic_acid

    Intake of large doses (2.0 to 4.0 g/day) of long-chain omega3 fatty acids as prescription drugs or dietary supplements are generally required to achieve significant (> 15%) lowering of triglycerides, and at those doses the effects can be significant (from 20% to 35% and even up to 45% in individuals with levels greater that 500 mg/dL).

  4. Eicosapentaenoic acid - Wikipedia

    en.wikipedia.org/wiki/Eicosapentaenoic_acid

    Intake of large doses (2.0 to 4.0 g/day) of long-chain omega3 fatty acids as prescription drugs or dietary supplements are generally required to achieve significant (> 15%) lowering of triglycerides, and at those doses the effects can be significant (from 20% to 35% and even up to 45% in individuals with levels greater than 500 mg/dL).

  5. Omega-3-carboxylic acids - Wikipedia

    en.wikipedia.org/wiki/Omega-3-carboxylic_acids

    Omega3-carboxylic acids are used in addition to changes in diet to reduce triglyceride levels in adults with severe (≥ 500 mg/dL) hypertriglyceridemia. [6]Intake of large doses (2.0 to 4.0 g/day) of long-chain omega3 fatty acids as prescription drugs or dietary supplements are generally required to achieve significant (> 15%) lowering of triglycerides, and at those doses the effects ...

  6. Antiarthritics - Wikipedia

    en.wikipedia.org/wiki/Antiarthritics

    Methotrexate is commonly associated with dose-related toxic effects involving the bone marrow and gastrointestinal tract. [12] Folic acid may be given weekly to help diminish the frequency of side-effects. [12] Methotrexate is also associated with acute and chronic liver damage. Other adverse effects include: [12] Life-threatening Interstitial ...

  7. Fish oil - Wikipedia

    en.wikipedia.org/wiki/Fish_oil

    To illustrate the amounts of EPA and DHA in supplements, a softgel capsule containing fish oil derived from pollock might contain a total of 642 mg of total fish oil, of which 584 mg are omega3 fatty acids, with 377 mg EPA and 158 mg DHA. 3 That same company's salmon oil softgel contains 1008 mg of total fish oil, of which 295 mg are omega ...

  8. Disease-modifying osteoarthritis drug - Wikipedia

    en.wikipedia.org/wiki/Disease-modifying...

    A disease-modifying osteoarthritis drug (DMOAD) is a disease-modifying drug that would inhibit or even reverse the progression of osteoarthritis. [1] Since the main hallmark of osteoarthritis is cartilage loss, a typical DMOAD would prevent the loss of cartilage and potentially regenerate it.

  9. Rofecoxib - Wikipedia

    en.wikipedia.org/wiki/Rofecoxib

    In September 2004, Merck voluntarily withdrew rofecoxib from the market because of concerns about increased risk of heart attack and stroke associated with long-term, high-dosage use. Merck withdrew the drug after disclosures that it withheld information about rofecoxib's risks from doctors and patients for over five years, allegedly resulting ...

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