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As of 2014, Biochimica et Biophysica Acta encompasses ten specialised sections with a total of 100 annual issues in ten volumes. Over 16,000 pages were published in 2011. The journal sections are published separately, with one annual volume per section (two for Reviews on Cancer), but form part of the volume numbering for Biochimica et Biophysica Acta.
Acta Biochimica et Biophysica Sinica was a Chinese-language journal entitled "Shengwu Huaxue Yu Shengwu Wuli Xuebao" (see box below), which began publishing sometime in 1958 or 1959, or August 1961, until December 2003 (depending on the source). Tables of contents were in English.
Genetically predicted low EPHX1 activity was associated with increased risk of developing tobacco-related cancer in smokers from 47089 Danish individuals . [46] Recent meta-analysis comprising 8,259 patients with chronic obstructive pulmonary disease (COPD) and 42,883 controls reported that the predicted slow activity EPHX1 phenotype is a ...
Proteasome subunit beta type-5 also known as 20S proteasome subunit beta-5 is a protein that in humans is encoded by the PSMB5 gene. [5] [6] [7] This protein is one of the 17 essential subunits (alpha subunits 1–7, constitutive beta subunits 1–7, and inducible subunits including beta1i, beta2i, beta5i) that contributes to the complete assembly of 20S proteasome complex.
TP63 encodes for two main isoforms by alternative promoters (TAp63 and ΔNp63). ΔNp63 is involved in multiple functions during skin development and in adult stem/progenitor cell regulation. [11] In contrast, TAp63 has been mostly restricted to its apoptotic function and more recently as the guardian of oocyte integrity. [12]
Reactions catalyzed by soluble epoxide hydrolase. The form of sEH in the intracellular environment is a homodimer with two distinct activities in two separate structural domains of each monomer: the C-terminal epoxide hydrolase activity (soluble epoxide hydrolase: EC 3.3.2.10) and the N-terminal phosphatase activity (lipid-phosphate phosphatase: EC 3.1.3.76).
TS's relation to the cell cycle also contributes to its use in cancer treatment. Several cell-cycle dependent kinases and transcription factors influence TS levels in the cell cycle that increase its activity during the S phase but decrease its activity while cells are no longer proliferating. [ 11 ]
18208 Ensembl ENSG00000065320 ENSMUSG00000020902 UniProt H7BZF4 O95631 O09118 RefSeq (mRNA) NM_004822 NM_008744 RefSeq (protein) NP_004813 NP_032770 Location (UCSC) Chr 17: 9.02 – 9.24 Mb Chr 11: 68.1 – 68.29 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Netrin-1 is a protein that in humans is encoded by the NTN1 gene. Netrin is included in a family of laminin-related secreted ...