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  2. Optic vesicle - Wikipedia

    en.wikipedia.org/wiki/Optic_vesicle

    These diverticula make their appearance before the closure of the anterior end of the neural tube; [1] [2] after the closure of the tube around the 4th week of development, they are known as the optic vesicles. Previous studies of optic vesicles suggest that the surrounding extraocular tissues – the surface ectoderm and extraocular mesenchyme ...

  3. Eye development - Wikipedia

    en.wikipedia.org/wiki/Eye_development

    Only the epidermis in the head is competent to respond to the signal from the optic vesicles. Both the optic vesicle and the head epidermis are required for eye development. The competence of the head epidermis to respond to the optic vesicle signals comes from the expression of Pax6 in the epidermis. Pax6 is necessary and sufficient for eye ...

  4. Optic stalk - Wikipedia

    en.wikipedia.org/wiki/Optic_stalk

    The optic vesicles project toward the sides of the head, and the peripheral part of each expands to form a hollow bulb, while the proximal part remains narrow and constitutes the optic stalk. [1] [2] Closure of the choroidal fissure in the optic stalk occurs during the seventh week of development. The former optic stalk is then called the optic ...

  5. List of optometric abbreviations - Wikipedia

    en.wikipedia.org/wiki/List_of_optometric...

    rule used to assess optic disc appearance K: Keratometry OS oculus sinister (left eye) LHyperT or LHT: Left hypertropia LHypoT: Left hypotropia LO: Lenticular opacity L/R FD: L/R fixation disparity L/R: L hyperphoria Left ET: Left esotropia LVA: Low vision aid MDU: Mallett distance unit MNU: Mallett near unit M.Wing: Maddox Wing: MR: Maddox rod ...

  6. Collie eye anomaly - Wikipedia

    en.wikipedia.org/wiki/Collie_eye_anomaly

    The choroid, especially lateral to the optic disc, is hypoplastic (underdeveloped). A coloboma, or hole, may form in or near the optic disc due to a failed closure of embryonic tissue. The degree of these abnormalities varies between individual dogs, and even between the same dog's eyes. [7]

  7. Optic cup (embryology) - Wikipedia

    en.wikipedia.org/wiki/Optic_cup_(embryology)

    During embryonic development of the eye, the outer wall of the bulb of the optic vesicles becomes thickened and invaginated, and the bulb is thus converted into a cup, the optic cup (or ophthalmic cup), consisting of two strata of cells.

  8. PAX6 - Wikipedia

    en.wikipedia.org/wiki/PAX6

    The vertebrate PAX6 locus encodes at least three different protein isoforms, these being the canonical PAX6, PAX6(5a), and PAX6(ΔPD).The canonical PAX6 protein contains an N-terminal paired domain, connected by a linker region to a paired-type homeodomain, and a proline/serine/threonine (P/S/T)-rich C-terminal domain.

  9. Optogenetics - Wikipedia

    en.wikipedia.org/wiki/Optogenetics

    Optogenetics is a biological technique to control the activity of neurons or other cell types with light. This is achieved by expression of light-sensitive ion channels, pumps or enzymes specifically in the target cells.

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