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  2. Diabetes alert dog - Wikipedia

    en.wikipedia.org/wiki/Diabetes_alert_dog

    The first dog trained to detect hypoglycemia was a Californian dog called Armstrong in 2003. [5] In 2009, a dog named Tinker from Durham City became the first self-taught British assistance dog to be officially registered for a type 2 diabetic owner. He was able to give his owner Paul Jackson up to half an hour warning before an attack occurred ...

  3. Diabetes in dogs - Wikipedia

    en.wikipedia.org/wiki/Diabetes_in_dogs

    The dog's body weight should be determined and calculated once every two weeks using weight scale. [48] The daily caloric requirement by the dog's body and BCS should also be determined using a scale as part of dietary management in maintaining average body weight. The protein intake by the dog should also be considered and checked twice a month.

  4. Pharmacokinetics - Wikipedia

    en.wikipedia.org/wiki/Pharmacokinetics

    Pharmacokinetics (from Ancient Greek pharmakon "drug" and kinetikos "moving, putting in motion"; see chemical kinetics), sometimes abbreviated as PK, is a branch of pharmacology dedicated to describing how the body affects a specific substance after administration. [1]

  5. Metformin - Wikipedia

    en.wikipedia.org/wiki/Metformin

    Metformin has acid dissociation constant values (pK a) of 2.8 and 11.5, so it exists very largely as the hydrophilic cationic species at physiological pH values. The metformin pK a values make it a stronger base than most other basic medications with less than 0.01% nonionized in blood.

  6. Area under the curve (pharmacokinetics) - Wikipedia

    en.wikipedia.org/wiki/Area_under_the_curve...

    For example, gentamicin is an antibiotic that can be nephrotoxic (kidney damaging) and ototoxic (hearing damaging); measurement of gentamicin through concentrations in a patient's plasma and calculation of the AUC is used to guide the dosage of this drug. [3] AUC becomes useful for knowing the average concentration over a time interval, AUC/t.

  7. When Is the Best Time to Take Metformin? - AOL

    www.aol.com/best-time-metformin-141700387.html

    We’ll guide you through the proper use of metformin. Here are the dos and don’ts for taking metformin tablets: Don’t chew or crush the tablets. Unless instructed by a healthcare professional ...

  8. Pyruvate kinase - Wikipedia

    en.wikipedia.org/wiki/Pyruvate_kinase

    Metformin, or dimethylbiguanide, is the primary treatment used for type 2 diabetes. Metformin has been shown to indirectly affect pyruvate kinase through the inhibition of gluconeogenesis. Specifically, the addition of metformin is linked to a marked decrease in glucose flux and increase in lactate/pyruvate flux from various metabolic pathways.

  9. Pet Rescue Saga walkthrough, cheats and tips - AOL

    www.aol.com/news/2013-04-25-pet-rescue-saga...

    Pet Rescue Saga is an action puzzle game created by King.com. Make your way through a variety of levels in this match-3 style adventure as you rescue pets from the malicious animal catchers!

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