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The effects of atropine on the central nervous system include memory disruption, which may lead to severe confusion. [74] The major effects of belladonna consumption last for three to four hours; visual hallucinations can last for three to four days, and some negative aftereffects are preserved for several days. [44]
The name Belladonna, meaning beautiful ladies, was derived from women using berry juice from the plant cosmetically to dilate their pupils. [ 4 ] The mydriatic effect was studied by the German chemist Friedlieb Ferdinand Runge (1795-1867), in which the active ingredient, atropine , was first discovered by Vaquelin in 1809 and was first isolated ...
The toxic berry of Atropa belladonna which contains the tropane deliriants scopolamine, atropine, and hyoscyamine.. Deliriants are a subclass of hallucinogen.The term was coined in the early 1980s to distinguish these drugs from psychedelics such as LSD and dissociatives such as ketamine, due to their primary effect of causing delirium, as opposed to the more lucid (i.e. rational thought is ...
Bellergal is a combination of levorotatory alkaloids of belladonna, ergotamine tartrate, and phenobarbital, [1] [2] used for the treatment of functional menopause, such as hot flashes and night sweat. Belladonna, including atropine, hyoscyamine and scopolamine, are antimuscarinic agents. They block acetylcholine from binding to its receptors.
The name "belladonna", Italian for "beautiful lady", is thought to derive from one of the antimuscarinic effects of these alkaloids: they were used by women for cosmetic purposes, to promote dilation of the pupils. [2] Muscarinic antagonist effects and muscarinic agonist effects counterbalance each other for homeostasis.
The formula [8] for the Towns-Lambert Alcoholism Cure, also known as the Belladonna Cure, was the deliriant Atropa belladonna, commonly known as belladonna or deadly nightshade. The effects of belladonna include delirium, hallucinations, light sensitivity, confusion, and dry mouth.
Hyoscyamine (also known as daturine or duboisine) is a naturally occurring tropane alkaloid and plant toxin. It is a secondary metabolite found in certain plants of the family Solanaceae, including henbane, mandrake, angel's trumpets, jimsonweed, the sorcerers' tree, and Atropa belladonna (deadly nightshade).
Anticholinergics generally have antisialagogue effects (decreasing saliva production), and most produce some level of sedation, both being advantageous in surgical procedures. [8] [9] Until the beginning of the 20th century, anticholinergic drugs were widely used to treat psychiatric disorders. [10]
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