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Clark's rule is a medical term referring to a mathematical formula used to calculate the proper dosage of medicine for children aged 2–17 based on the weight of the patient and the appropriate adult dose. [1] The formula was named after Cecil Belfield Clarke (1894–1970), a Barbadian physician who practiced throughout the UK, the West Indies ...
Treatment of these functional causes can be focused on simply relieving the symptoms. [6] Studies have shown a link between diets low in dietary fibres and high in processed foods, such as fast food, and childhood constipation. [7] Certain medications such as antacids, anticholinergics and opiates are also known to cause constipation in ...
Senna glycoside, also known as sennoside or senna, is a medication used to treat constipation and empty the large intestine before surgery. [1] [5] The medication is taken by mouth or via the rectum. [1] [6] It typically begins working in around 30 minutes when given by rectum and within twelve hours when given by mouth. [3]
Constipation is more concerning when there is weight loss or anemia, blood is present in the stool, there is a history of inflammatory bowel disease or colon cancer in a person's family, or it is of new onset in someone who is older. [12] Treatment of constipation depends on the underlying cause and the duration that it has been present. [4]
Macrogol 4000, pharmaceutical quality. Macrogol 3350, often in combination with electrolytes, is used for short-term relief of constipation as well as for long-term use in constipation of various causes, including in multiple sclerosis and Parkinson's disease patients (an often-overlooked non-motor symptom) as well as constipation caused by pharmaceutical drugs such as opioids and ...
On May 12, 1868, the United States Patent Office granted a patent to Dr. Samuel Pitcher (1824-1907) of Barnstable, Massachusetts, for a cathartic composed of senna, sodium bicarbonate, essence of wintergreen, dandelion, sugar and water. [1]
Pharmacological treatment for children with functional constipation consists of maintenance therapy and faecal disimpaction. High-dose oral polyethylene glycol (PEG) or enemas containing active substances can induce fecal disimpaction, while maintenance therapy is recommended after successful disimpaction to avoid reoccurring stool buildup.
Linaclotide is indicated to treat irritable bowel syndrome with constipation and chronic constipation with no known cause. [ 4 ] [ 3 ] In June 2023, the indication was expanded in the US to include the treatment of functional constipation .
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