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A study into the effects of the benzodiazepine receptor antagonist, flumazenil, on benzodiazepine withdrawal symptoms persisting after withdrawal was carried out by Lader and Morton. Study subjects had been benzodiazepine-free for between one month and five years, but all reported persisting withdrawal effects to varying degrees.
Post-acute withdrawal syndrome (PAWS) is a hypothesized set of persistent impairments that occur after withdrawal from alcohol, [ 1 ][ 2 ] opiates, benzodiazepines, antidepressants, and other substances. [ 3 ][ 4 ][ 5 ] Infants born to mothers who used substances of dependence during pregnancy may also experience a PAWS. [ 6 ][ 7 ] While PAWS ...
In the elderly, long-term benzodiazepine therapy is a risk factor for amplifying cognitive decline, [29] although gradual withdrawal is associated with improved cognitive status. [30] A study of alprazolam found that 8 weeks administration of alprazolam resulted in deficits that were detectable after several weeks but not after 3.5 years.
Failure to treat benzodiazepine dependence in the elderly can cause serious medical complications. [14] The elderly have less cognitive reserve and are more sensitive to the short (e.g., in between dose withdrawal) and protracted withdrawal effects of benzodiazepines, as well as the side-effects both from short-term and long-term use. This can ...
Stress can lead to a rash, such as hives, and it can exacerbate other rash-like skin conditions, Hu says. The link between stress and skin goes back to the hypothalamic-pituitary-adrenal axis in ...
Alprazolam, sold under the brand name Xanax and others, is a fast-acting, potent tranquilizer of moderate duration within the triazolobenzodiazepine group of chemicals called benzodiazepines. [ 15 ] Alprazolam is most commonly prescribed in the management of anxiety disorders, especially panic disorder and generalized anxiety disorder (GAD). [ 9 ]
You might experience common side effects. There are common side effects associated with most medications, including alprazolam. Some adverse effects to be aware of are: Alternatives to Xanax for Sleep
Parkinson’s disease and Alzheimer’s disease risk are lowered in people who take a type of type 2 diabetes drug, a study from South Korea has shown. Researchers from Yonsei University College ...