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IDDM11. Insulin-dependent (type I) diabetes mellitus (IDDM) is a genetic heterogenouse autoimmune disorder, which is triggered by genetic predisposition and environmental factors. [1] The prevalence of insulin-dependent (type I) diabetes mellitus (IDDM) among children and young adult from Europe is approximately 0.4%. [2]
Endocrinology. Complications of diabetes are secondary diseases that are a result of elevated blood glucose levels that occur in diabetic patients. These complications can be divided into two types: acute and chronic. Acute complications are complications that develop rapidly and can be exemplified as diabetic ketoacidosis (DKA), hyperglycemic ...
Many drugs impair insulin secretion and some toxins damage pancreatic beta cells, whereas others increase insulin resistance (especially glucocorticoids which can provoke "steroid diabetes"). The ICD-10 (1992) diagnostic entity, malnutrition-related diabetes mellitus (ICD-10 code E12), was deprecated by the World Health Organization (WHO) when ...
Diabetic cardiomyopathy is a disorder of the heart muscle in people with diabetes. It can lead to inability of the heart to circulate blood through the body effectively, a state known as heart failure (HF), [ 2] with accumulation of fluid in the lungs ( pulmonary edema) or legs ( peripheral edema ). Most heart failure in people with diabetes ...
Frequency. 4–25% of people with type 1 diabetes per year [ 1][ 5] Diabetic ketoacidosis ( DKA) is a potentially life-threatening complication of diabetes mellitus. [ 1] Signs and symptoms may include vomiting, abdominal pain, deep gasping breathing, increased urination, weakness, confusion and occasionally loss of consciousness. [ 1]
Pre-gestational diabetes can be classified as Type 1 or Type 2 depending on the physiological mechanism. Type 1 diabetes mellitus is an autoimmune disorder leading to destruction of insulin-producing cell in the pancreas; type 2 diabetes mellitus is associated with obesity and results from a combination of insulin resistance and insufficient insulin production.
Slowly evolving immune-mediated diabetes, or latent autoimmune diabetes in adults ( LADA ), is a form of diabetes that exhibits clinical features similar to both type 1 diabetes (T1D) and type 2 diabetes (T2D), [ 3][ 4] and is sometimes referred to as type 1.5 diabetes. [ 5] It is an autoimmune form of diabetes, similar to T1D, but patients ...
Diabetic angiopathy. Diabetic angiopathy is a form of angiopathy associated with diabetic complications. [ 1] While not exclusive, the two most common forms are diabetic retinopathy and diabetic nephropathy, whose pathophysiologies are largely identical. Other forms of diabetic angiopathy include diabetic neuropathy and diabetic cardiomyopathy ...