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  2. Hormone receptor positive breast tumor - Wikipedia

    en.wikipedia.org/wiki/Hormone_receptor_positive...

    ER-positive is one of the Receptor statuses identified in the classification of breast cancer.Receptor status was traditionally considered by reviewing each individual receptor (ER, PR, her2) in turn, but newer approaches look at these together, along with the tumor grade, to categorize breast cancer into several conceptual molecular classes [1] that have different prognoses [2] and may have ...

  3. HER2 - Wikipedia

    en.wikipedia.org/wiki/HER2

    HER2 is a member of the human epidermal growth factor receptor (HER/EGFR/ERBB) family. But contrary to other members of the ERBB family, HER2 does not directly bind ligand. HER2 activation results from heterodimerization with another ERBB member or by homodimerization when HER2 concentration are high, for instance in cancer. [8]

  4. Endocrine therapy resistance in breast cancer - Wikipedia

    en.wikipedia.org/wiki/Endocrine_therapy...

    The overexpression of HER2 is determined by immunohistochemistry (IHC), or with fluorescent in situ hybridization in those equivocal cases where IHC does not provide a clear result. Different molecular subtypes of breast cancer have also been described, which loosely align with receptor status: Luminal A (ER and/or PR positive; HER2 negative)

  5. Breast cancer management - Wikipedia

    en.wikipedia.org/wiki/Breast_cancer_management

    Staging breast cancer is the initial step to help physicians determine the most appropriate course of treatment. As of 2016, guidelines incorporated biologic factors, such as tumor grade, cellular proliferation rate, estrogen and progesterone receptor expression, human epidermal growth factor 2 (HER2) expression, and gene expression profiling into the staging system.

  6. 7 major questions about alcohol and cancer: What doctors ...

    www.aol.com/surgeon-generals-suggestion-put...

    A report from the U.S. surgeon general suggested that labels on alcoholic drinks should warn about cancer risk. Doctors expressed their agreement. For people wondering about the long-term damage ...

  7. Breast cancer - Wikipedia

    en.wikipedia.org/wiki/Breast_cancer

    This is an accepted version of this page This is the latest accepted revision, reviewed on 2 January 2025. Cancer that originates in mammary glands Medical condition Breast cancer An illustration of breast cancer Specialty Surgical Oncology Symptoms A lump in a breast, a change in breast shape, dimpling of the skin, fluid from the nipple, a newly inverted nipple, a red scaly patch of skin on ...

  8. Annuity vs IRA: Which Vehicle Is Actually Better for Your ...

    www.aol.com/annuity-vs-ira-vehicle-actually...

    Still, it does come with the upside of more growth potential, so there is a big question of which vehicle you are more comfortable with. Long-Term Retirement Strategy

  9. What is the Mayo Clinic Diet — and is it healthy? - AOL

    www.aol.com/lifestyle/mayo-clinic-diet-does...

    The Mayo Clinic Diet focuses on building new healthy habits and breaking old, less-healthy habits to help with weight loss and overall health.

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