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  2. Merck's (MRK) Keytruda Gets Nod for Esophageal Cancer in EU - AOL

    www.aol.com/news/mercks-mrk-keytruda-gets-nod...

    Merck's (MRK) Keytruda gets approval in combination with chemotherapy in first-line setting for advanced esophageal and HER2-negative GEJ cancer based on data from the phase III KEYNOTE-590 study

  3. Merck's Keytruda Phase 3 Trial Meets Primary Endpoint In ...

    www.aol.com/news/mercks-keytruda-phase-3-trial...

    Merck & Co Inc (NYSE: MRK) has announced topline results from the pivotal Phase 3 KEYNOTE-859 trial of its flagship anti-PD-1 therapy, Keytruda, in gastric or Gastroesophageal Junction GEJ ...

  4. Pembrolizumab - Wikipedia

    en.wikipedia.org/wiki/Pembrolizumab

    Pembrolizumab, sold under the brand name Keytruda, is a humanized antibody, more specifically a PD-1 inhibitor, used in cancer immunotherapy that treats melanoma, lung cancer, head and neck cancer, Hodgkin lymphoma, stomach cancer, cervical cancer, and certain types of breast cancer. [12] [14] [15] [16] It is administered by slow intravenous ...

  5. Gastrointestinal cancer - Wikipedia

    en.wikipedia.org/wiki/Gastrointestinal_cancer

    Cancer of the esophagus is often detected late inasmuch as there are typically no early symptoms. Nevertheless, if the cancer is caught soon enough, patients can have a five-year survival rate of 90% or above. By the time esophageal cancer is usually detected, though, it might have spread beyond the esophageal wall, and the survival rate drops ...

  6. Merck's (MRK) Keytruda Gets Nod for Esophageal Cancer in EU ...

    www.aol.com/news/mercks-mrk-keytruda-gets-nod...

    Merck's (MRK) Keytruda gets approval in combination with chemotherapy in first-line setting for advanced esophageal and HER2-negative GEJ cancer based on data from the phase III KEYNOTE-590 study

  7. Oesophagogastric junctional adenocarcinoma - Wikipedia

    en.wikipedia.org/wiki/Oesophagogastric_junction...

    Oesophagogastric junctional adenocarcinoma (OGJ adenocarcinoma) is a cancer of the lower part of the oesophagus with a rising incidence in Western countries. [1] This disease is often linked to Barrett's oesophagus. H&E stain of esophageal adenocarcinoma

  8. Merck (MRK) Keytruda Advanced Gastric Cancer Study ... - AOL

    www.aol.com/news/merck-mrk-keytruda-advanced...

    Per management, advanced gastric cancer has one of the lowest five-year survival rates. The results from the KEYNOTE-859 study show that Keytruda plus chemotherapy improves survival beyond ...

  9. Checkpoint inhibitor - Wikipedia

    en.wikipedia.org/wiki/Checkpoint_inhibitor

    It was approved in 2014. Nivolumab is approved to treat melanoma, lung cancer, kidney cancer, bladder cancer, head and neck cancer, and Hodgkin's lymphoma. [16] Pembrolizumab (brand name Keytruda) is another PD-1 inhibitor that was approved by the FDA in 2014 and was the second checkpoint inhibitor approved in the United States. [17]