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Oral fosfomycin is not recommended for children under 12 years old. [15] Additional uses have been proposed. [16] The global problem of advancing antimicrobial resistance has led to a renewed interest in its use more recently. [17] Fosfomycin can be used as an efficacious treatment for both UTIs and complicated UTIs including acute pyelonephritis.
Chemical structure of fosfomycin. Fosfomycin is a phosphonic acid bactericidal agent. It is commonly used as the first-line treatment for acute simple cystitis, demonstrating a 91% cure rate. [4] [9] It is administered orally as a single dose; In more complicated UTIs, the dose is adjusted to be repeated every three days to achieve successful ...
The selection and use of essential medicines: report of the WHO Expert Committee, 2017 (including the 20th WHO Model List of Essential Medicines and the 6th Model List of Essential Medicines for Children). Geneva: World Health Organization. hdl: 10665/259481. ISBN 978-92-4-121015-7. ISSN 0512-3054. WHO technical report series; no. 1006.
Fosfomycin can be used as an effective treatment for both UTIs and complicated UTIs including acute pyelonephritis. [87] The standard regimen for complicated UTIs is an oral 3g dose administered once every 48 or 72 hours for a total of 3 doses or a 6 grams every 8 hours for 7 days to 14 days when fosfomycin is given in IV form. [87]
[20] A separate list for children up to 12 years of age, known as the WHO Model List of Essential Medicines for Children (EMLc), was created in 2007 and is in its 9th edition. [10] [21] [22] [23] It was created to make sure that the needs of children were systematically considered such as availability of proper formulations.
The average age for perimenopause in the U.S. is around 47 years old, and while the average duration of perimenopause is four years, it can range from eight to 10, according to the Cleveland ...
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Fosfomycin: Monurol, Monuril: Acute cystitis in women: This antibiotic is not recommended for children and 75 and up of age: Inactivates enolpyruvyl transferase, thereby blocking cell wall synthesis Fusidic acid: Fucidin: Metronidazole: Flagyl: Infections caused by anaerobic bacteria; also amoebiasis, trichomoniasis, giardiasis