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Superior vena cava syndrome (SVCS), is a group of symptoms caused by obstruction of the superior vena cava ("SVC"), a short, wide vessel carrying circulating blood into the heart. The majority of cases are caused by malignant tumors within the mediastinum , most commonly lung cancer and non-Hodgkin's lymphoma , directly compressing or invading ...
A positive Pemberton's sign is indicative of superior vena cava syndrome (SVC), commonly the result of a mass in the mediastinum.Although the sign is most commonly described in patients with substernal goiters where the goiter "corks off" the thoracic inlet, [4] the maneuver is potentially useful in any patient with adenopathy, tumor, or fibrosis involving the mediastinum.
Superior vena cava obstruction refers to a partial or complete obstruction of the superior vena cava, typically in the context of cancer such as a cancer of the lung, metastatic cancer, or lymphoma. Obstruction can lead to enlarged veins in the head and neck, and may also cause breathlessness, cough, chest pain, and difficulty swallowing.
If obstruction of the superior vena cava by the Pancoast tumor occurs, a resulting mass effect called the superior vena cava syndrome occurs, resulting in facial swelling cyanosis and dilatation of the veins of the head and neck. This syndrome can be seen in 5-10% of patient cases. [11]
The left superior vena cava is not shown in this image. In anatomy , a persistent left superior vena cava is the most common variation of the thoracic venous system . [ 1 ] [ 2 ] It is present in between 0.3% and 0.5% of the population, [ 3 ] [ 4 ] [ 5 ] and is an embryologic remnant that results from a failure to involute .
If this vein fails to disappear, the persistent left superior vena cava will form. [13] This anomaly is present in between 0.3% and 0.5% of the population and roughly 2.1% to 4.3% of those with congenital heart disease. [3] Usually babies who experience the persistence of a left superior vena cava display other heart anomalies as well. [13]
In anatomy, the venae cavae (/ ˈ v iː n i ˈ k eɪ v i /; [1] sg.: vena cava / ˈ v iː n ə ˈ k eɪ v ə /; from Latin 'hollow veins') [2] are two large veins (great vessels) that return deoxygenated blood from the body into the heart. In humans they are the superior vena cava and the inferior vena cava, and both empty into the right atrium ...
Non-developmental syndromes also directly or indirectly affect the Great Cerebral Vein of Galen, although they are extremely rare. These include superior vena cava syndrome (SVCS), and thrombosis of the lateral sinus, superior sagittal sinus, internal jugular vein, or of the Great Cerebral Vein of Galen itself. [citation needed]
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