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Normal cervical cells in a Pap smear. In the conventional Pap smear, the collected cells are smeared on a microscope slide, and a fixative is applied. The slide is evaluated in a pathology lab to identify cellular abnormalities. Accuracy of conventional cytology report: [10] sensitivity: 55% to 88%; specificity: 71% to 94%
The Papanicolaou test (abbreviated as Pap test, also known as Pap smear (AE), [1] cervical smear (BE), cervical screening (BE), [2] or smear test (BE)) is a method of cervical screening used to detect potentially precancerous and cancerous processes in the cervix (opening of the uterus or womb) or, more rarely, anus (in both men and women). [3]
Papanicolaou stain (also Papanicolaou's stain and Pap stain) is a multichromatic (multicolored) cytological staining technique developed by George Papanicolaou in 1942. [ 1 ] [ 2 ] [ 3 ] The Papanicolaou stain is one of the most widely used stains in cytology , [ 1 ] where it is used to aid pathologists in making a diagnosis.
Per the expert, there’s no one-size-fits-all answer to this—namely because how often women should get a pap smear depends on their age and gynecologic history.
Getting a Pap smear isn’t high on most people’s list, but it’s the go-to test to look for cervical changes that could lead to cancer. So, most women endure it every three or so years. So ...
Depending on patient's age or Pap smear result, HPV testing may also be performed. Sexually transmitted infection screening - Depending on age and risk factors, clinicians may recommend gonorrhea or chlamydia testing at the time of the well-woman exam. This sample can be collected via a swab of the cervix or vagina.
The Pap test is still widely used as a means of early cancer detection and is estimated to have reduced fatalities caused by cancer of the reproductive systems in women by half. [10] By some accounts, the pap test is considered the most significant advance in the control of cancer in the 20th century.
Because of the link between HPV and cervical cancer, the ACS currently recommends early detection of cervical cancer in average-risk asymptomatic adults primarily with cervical cytology by Pap smear, regardless of HPV vaccination status. Women aged 30–65 should preferably be tested every 5 years with both the HPV test and the Pap test.