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Necrotizing pneumonia (NP), also known as cavitary pneumonia or cavitatory necrosis, is a rare but severe complication of lung parenchymal infection. [ 1 ] [ 2 ] [ 3 ] In necrotizing pneumonia, there is a substantial liquefaction following death of the lung tissue, which may lead to gangrene formation in the lung.
Necrotizing pneumonia (NP), also known as cavitary pneumonia or cavitatory necrosis, is a rare but severe complication of lung parenchymal infection. [ 5 ] [ 6 ] [ 7 ] In necrotizing pneumonia, there is a substantial liquefaction following death of the lung tissue, which may lead to gangrene formation in the lung.
Necrotizing pneumonia [5] Vasculitis: Granulomatosis with polyangiitis; Necrotizing tumors: 8% to 18% are due to neoplasms across all age groups, higher in older people; primary squamous carcinoma of the lung is the most common.
The genus Klebsiella was named after the German microbiologist Edwin Klebs (1834–1913). [citation needed] It is also known as Friedlander's bacillum in honor of Carl Friedländer, a German pathologist, who proposed that this bacterium was the etiological factor for the pneumonia seen especially in immunocompromised individuals such as people with chronic diseases or alcoholics.
Pneumonia fills the lung's alveoli with fluid, hindering oxygenation. The alveolus on the left is normal, whereas the one on the right is full of fluid from pneumonia. Pneumonia frequently starts as an upper respiratory tract infection that moves into the lower respiratory tract. [55] It is a type of pneumonitis (lung inflammation). [56]
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Progression of the infection from pneumonitis into necrotizing pneumonia and pulmonary abscess can occur, with or without the development of empyema. [ 22 ] [ 23 ] The infection is often polymicrobial in nature and isolates of community-acquired infection (in 60–80% of cases) are aerobic and anaerobic belonging to the individual's ...