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Diagram showing venous blood flow from capillary beds in some specific locations including the lungs, liver, and kidneys. There are some separate parallel systemic circulatory routes that supply specific regions, and organs. [8] They include the coronary circulation, the cerebral circulation, the bronchial circulation, and the renal circulation.
Venous return (VR) is the flow of blood back to the heart. Under steady-state conditions, venous return must equal cardiac output (Q), when averaged over time because the cardiovascular system is essentially a closed loop. Otherwise, blood would accumulate in either the systemic or pulmonary circulations.
The human hepatic portal system delivers about three-fourths of the blood going to the liver.The final common pathway for transport of venous blood from spleen, pancreas, gallbladder and the abdominal portion of the gastrointestinal tract [2] (with the exception of the inferior part of the anal canal and sigmoid colon) is through the hepatic portal vein.
The hepatic vein subsequently drains into the inferior vena cava. The hepatic artery provides 30 to 40% of the oxygen to the liver, while only accounting for 25% of the total liver blood flow. The rest comes from the partially deoxygenated blood from the portal vein. The liver consumes about 20% of the total body oxygen when at rest.
Cerebral blood flow (CBF) is the blood supply to the brain in a given period of time. [8] In an adult, CBF is typically 750 millilitres per minute or 15.8 ± 5.7% of the cardiac output . [ 9 ] This equates to an average perfusion of 50 to 54 millilitres of blood per 100 grams of brain tissue per minute.
Thus he apparently postulated capillaries but with reversed flow of blood. [citation needed] In 2nd-century AD Rome, the Greek physician Galen knew that blood vessels carried blood and identified venous (dark red) and arterial (brighter and thinner) blood, each with distinct and separate functions. Growth and energy were derived from venous ...
Approximately 75% of hepatic blood flow is derived from the portal vein, while the remainder is from the hepatic arteries. [4] Unlike most veins, the portal vein does not drain into the heart. Rather, it is part of a portal venous system that delivers venous blood into another capillary system, the hepatic sinusoids of the liver.
Venous blood is typically colder than arterial blood, [1] and has a lower oxygen content and pH. It also has lower concentrations of glucose and other nutrients and has higher concentrations of urea and other waste products. The difference in the oxygen content of arterial blood and venous blood is known as the arteriovenous oxygen difference.