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2. Sildenafil - Wikipedia

   en.wikipedia.org/wiki/Sildenafil

   Sildenafil, sold under the brand name Viagra among others, is a medication used to treat erectile dysfunction and pulmonary arterial hypertension. [ 4 ] [ 8 ] It is also sometimes used off-label for the treatment of certain symptoms in secondary Raynaud's phenomenon . [ 9 ]

3. PDE5 inhibitor - Wikipedia

   en.wikipedia.org/wiki/PDE5_inhibitor

   Chemical structure of sildenafil (Viagra), the prototypical PDE5 inhibitor. A phosphodiesterase type 5 inhibitor (PDE5 inhibitor) is a vasodilating drug that works by blocking the degradative action of cGMP-specific phosphodiesterase type 5 (PDE5) on cyclic GMP in the smooth muscle cells lining the blood vessels supplying various tissues.

4. 4 Surprising Uses of Viagra (Including What It Was Really ...

   www.aol.com/4-surprising-uses-viagara-including...

   Sildenafil can still be used to treat hypertension, but today, the primary use of this PDE5 inhibitor is to remedy ED. Other first-line treatment options for blood pressure and heart disease are ...

5. Is Sildenafil Safe for This Common Male Problem? - AOL

   www.aol.com/sildenafil-safe-common-male-problem...

   After further trials, sildenafil citrate was approved by the Food and Drug Administration (FDA) in 1998 as the active ingredient in brand name Viagra, now a very well-known drug for ED.

6. What Happens If You Take Viagra and You Don't Need It? - AOL

   www.aol.com/happens-viagra-dont-105800158.html

   Recreational Viagra use does happen, and while some men see harmless benefits from the active ingredient in the famous “little blue pill,” they’re still taking a significant risk every time ...

7. Drugs in pregnancy - Wikipedia

   en.wikipedia.org/wiki/Drugs_in_pregnancy

   Until 2014, the U.S. Code of Federal Regulations required that certain drugs and biological products be labelled specifically with respect to their effects on pregnant populations, including a definition of a "pregnancy category". These rules were enforced by the FDA, and medications that have been studied for their effects in pregnancy fell ...

8. What Does Viagra Actually Do to Your "Intimate" Experience? - AOL

   www.aol.com/does-viagra-actually-intimate...

   In clinical trials of Viagra, more than 82 percent of men with ED reported an improvement in their climaxes after using Viagra at a dosage of 100mg (the highest dosage prescribed for ED).

9. Vardenafil - Wikipedia

   en.wikipedia.org/wiki/Vardenafil

   Vardenafil's indications and contraindications are the same as with other PDE5 inhibitors; it is closely related in function to sildenafil citrate (Viagra) and tadalafil (Cialis). The difference between the vardenafil molecule and sildenafil citrate is a nitrogen atom's position and the change of sildenafil's piperazine ring methyl group to an ...