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Lugol's iodine has been used traditionally to replenish iodine deficiency. Because of its wide availability as a drinking-water decontaminant, and high content of potassium iodide, emergency use of it was at first recommended to the Polish government in 1986, after the Chernobyl disaster to replace and block any intake of radioactive 131
However, since iodine has moderate solubility in ethanol, it is also assisted by this solvent directly. Lugol's iodine, by contrast, has no alcohol, and has twice the mass of potassium iodide as of elemental iodine. Alcohol content in the tincture of iodine can be determined by the methods of Alcock, Roscoe – Schorlemmer and Thurston ...
The image on the right stains with Lugol's iodine, and identifies a squamous cell carcinoma, which does not pick up the stain. Chromoendoscopy is a medical procedure wherein dyes (often the same stains used in histology ) are instilled into the gastrointestinal tract at the time of visualization with fibre-optic endoscopy .
Tincture of iodine: iodine in ethanol, or iodine and sodium iodide in a mixture of ethanol and water. Lugol's iodine: iodine and iodide in water alone, forming mostly triiodide. Unlike tincture of iodine, Lugol's iodine has a minimised amount of the free iodine (I 2) component. Iodine glycerin, a preparation used in dentistry.
This allows Lugol's iodine to be produced in strengths varying from 2% to 15% iodine. Elemental iodine (I 2) is poisonous if taken orally in large amounts; 2–3 grams is a lethal dose for an adult human. [71] [72] Iodine vapor is very irritating to the eye, to mucous membranes, and in the respiratory tract.
These dosages list mass of potassium iodide rather than elemental iodine. [17] [16] Potassium iodide can be administered as tablets or as Lugol's iodine solution. [16] The same dosage is recommended by the US Food and Drug Administration. [18] A single daily dose is typically sufficient for 24-hour protection. [16]
Lugol's iodine contains potassium iodide and a stoichiometric amount of elemental iodine, so that significant amounts of triiodide ion exist in this solution. Tincture of iodine, although nominally a solution of elemental iodine in ethanol, also contains significant amounts of triiodide, due to its content of both iodide and water.
Lugol's solution or Lugol's iodine (IKI) is a brown solution that turns black in the presence of starches and can be used as a cell stain, making the cell nuclei more visible. Used with common vinegar (acetic acid), Lugol's solution is used to identify pre-cancerous and cancerous changes in cervical and vaginal tissues during "Pap smear" follow ...
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