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The price of a vial of Eli Lilly’s Humalog has risen by more than 1,000 percent over the past 20 years.
An injector pen consists of a chamber or cartridge of medication, a tip to attach a needle, and a piston or plunger to inject the dose. [4] Some pens, including most insulin pens, include dials to adjust the dose of the injection before each administration. [2]
A portable drug-delivery device, comprising an insulin container (prefilled for disposable pens, or refillable with cartridges); a dialing system to select the dose (in increments of 0.5 or 1 Unit); and a button which delivers the drug when pressed; disposable needles are attached prior to each use. To administrate insulin under the skin. [10]
Insulin lispro was first approved for use in the United States in 1996. [5] [8] [9] It is a manufactured analogue of human insulin where two amino acids have swapped positions. [10] In 2022, it was the 70th most commonly prescribed medication in the United States, with more than 9 million prescriptions. [11] [12]
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In 2022, it was the 192nd most commonly prescribed medication in the United States, with more than 2 million prescriptions. [9] [10] Insulin can be made from the pancreas of pigs or cows. [11] Human versions can be made either by modifying pig versions, or recombinant technology [11] using mainly E. coli or Saccharomyces cerevisiae. [12]
Insulin is a molecule that tells the body to move sugar from the blood into cells, where it can be used for energy. People with Type 1 diabetes must therefore take insulin, because their bodies ...
Insulin glargine was patented, but the patent expired in most jurisdictions in 2014. It was approved for medical use in the United States in 2000. [7] It is on the World Health Organization's List of Essential Medicines. [9] In 2022, it was the 28th most commonly prescribed medication in the United States, with more than 18 million prescriptions.
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