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Topical drug delivery (TDD) is a route of drug administration that allows the topical formulation to be delivered across the skin upon application, hence producing a localized effect to treat skin disorders like eczema. [1] [2] The formulation of topical drugs can be classified into corticosteroids, antibiotics, antiseptics, and anti-fungal.
Topical drug delivery is a route of administering drugs via the skin to provide topical therapeutic effects. As skin is one of the largest and most superficial organs in the human body, pharmacists utilise it to deliver various drugs. This system usually provides a local effect on certain positions of the body.
Routes can also be classified based on where the target of action is. Action may be topical (local), enteral (system-wide effect, but delivered through the gastrointestinal tract), or parenteral (systemic action, but is delivered by routes other than the GI tract). Route of administration and dosage form are aspects of drug delivery.
Rising Demand for Non-Invasive Therapeutics: The Topical Drug Delivery Market is witnessing increased demand due to a rising preference for non-invasive treatment methods. Patients prefer drug delivery systems that circumvent the intricacies of injections or oral medications, prompting innovation in creams, gels, and patches.
The drug can penetrate deeply into the skin [2] and be directly delivered to the target site, as the topical application allows it to avoid hepatic first pass metabolism. [ 1 ] [ 2 ] [ 8 ] [ 6 ] Difficulties in gastrointestinal absorption caused by pH, enzymatic activity and drug-food interactions can be minimized, while at the same time ...
An advantage of a transdermal drug delivery route over other types of medication delivery (such as oral, topical, intravenous, or intramuscular) is that the patch provides a controlled release of the medication into the patient, usually through either a porous membrane covering a reservoir of medication or through body heat melting thin layers ...
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