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A mediastinal tumor is a tumor in the mediastinum, the cavity that separates the lungs from the rest of the chest. It contains the heart , esophagus , trachea , thymus , and aorta . The most common mediastinal masses are thymoma (20% of mediastinal tumors), usually found in the anterior mediastinum, followed by neurogenic Timor (15–20% ...
The diagnosis of a mediastinal germ cell tumor should be considered in all young males with a mediastinal mass. In addition to physical examination and routine laboratory studies, initial evaluation should include CT of the chest and abdomen, and determination of serum levels of HCG and alpha-fetoprotein.
The principle of surgical resection in limited‐stage small cell lung carcinoma aimed to remove all viable tumors with curative intent. [17] Consideration of surgery is recommended for Stage 1 limited-stage small cell lung cancer patient with a solitary nodule, no hilar or mediastinal involvement, absence of distant metastases , and no ...
Mediastinal shift is an abnormal movement of the mediastinal structures toward one side of the chest cavity. A shift indicates a severe imbalance of pressures inside the chest. [ 1 ] Mediastinal shifts are generally caused by increased lung volume, decreased lung volume, or abnormalities in the pleural space.
AMKL associated with mediastinal germ cell tumors typically occurs in younger adults, i.e. ages 13–36 (average age 24). [1] Cases occurring in children aged ≤18 years, which represent ~20% of all cases, could be regarded in the non-DS-AMKL category. [20] Cases of the disease not associated with mediastinal germ cell tumors occur in adults ...
Small-cell lung carcinoma (SCLC) has long been divided into two clinicopathological stages, termed limited stage (LS) and extensive stage (ES). [8] The stage is generally determined by the presence or absence of metastases, whether or not the tumor appears limited to the thorax, and whether or not the entire tumor burden within the chest can feasibly be encompassed within a single radiotherapy ...
The mediastinum (from Medieval Latin: mediastinus, lit. 'midway'; [2] pl.: mediastina) is the central compartment of the thoracic cavity.Surrounded by loose connective tissue, it is a region that contains vital organs and structures within the thorax, namely the heart and its vessels, the esophagus, the trachea, the vagus, phrenic and cardiac nerves, the thoracic duct, the thymus and the lymph ...
The analysis of tumor markers also helps in staging. [12] The preferred treatment for most forms of stage 1 seminoma is active surveillance. Stage 1 seminoma is characterized by the absence of clinical evidence of metastasis. Active surveillance consists of periodic history and physical examinations, tumor marker analysis, and radiographic imaging.