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The bunker experiment was a scientific experiment that began in 1966 to test whether humans, like other species, have an intrinsic circadian clock. [1] It was started by Jürgen Aschoff and Rütger Wever of the Max Planck Institute for Behavioral Physiology and later taken over by Jürgen Zulley.
A circadian rhythm (/ s ər ˈ k eɪ d i ə n /), or circadian cycle, is a natural oscillation that repeats roughly every 24 hours. Circadian rhythms can refer to any process that originates within an organism (i.e., endogenous ) and responds to the environment (is entrained by the environment).
In vertebrates, the master circadian clock is contained within the suprachiasmatic nucleus (SCN), a bilateral nerve cluster of about 20,000 neurons. [10] [11] The SCN itself is located in the hypothalamus, a small region of the brain situated directly above the optic chiasm, where it receives input from specialized photosensitive ganglion cells in the retina via the retinohypothalamic tract.
Any biological process in the body that repeats itself over a period of approximately 24 hours and maintains this rhythm in the absence of external stimuli is considered a circadian rhythm. [4] It is believed that the brain's suprachiasmatic nucleus (SCN), or internal pacemaker, is responsible for regulating the body's biological rhythms ...
Circadian disruption is a brief or long period of interference within a circadian rhythm. Chronodisturbance is the disruption of a circadian rhythm which leads to adaptive changes, leading to a less substantial negative impact in comparison to chronodisruption, which leads to disease. [40] Another notable researcher in the field is Mary E ...
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The best studied rhythm in chronobiology is the circadian rhythm, a roughly 24-hour cycle shown by physiological processes in all these organisms. The term circadian comes from the Latin circa, meaning "around" and dies, "day", meaning "approximately a day." It is regulated by circadian clocks.
A circadian rhythm is an entrainable, endogenous, biological activity that has a period of roughly twenty-four hours. This internal time-keeping mechanism is centralized in the suprachiasmatic nucleus (SCN) of humans, and allows for the internal physiological mechanisms underlying sleep and alertness to become synchronized to external environmental cues, like the light-dark cycle. [4]