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ALS is a motor neuron disease, which is a group of neurological disordersthat selectively affect motor neurons, the cells that control voluntary musclesof the body.[3] Other motor neuron diseases include primary lateral sclerosis(PLS), progressive muscular atrophy(PMA), progressive bulbar palsy, pseudobulbar palsy, and monomelic amyotrophy(MMA).
BFS can also be caused by long-term use of anticholinergics, [4] and fasciculations may be caused by other drug use or exposure to steroids, nicotine, caffeine, alcohol, insecticides and pesticides. [2] Thyroid disease may also cause similar symptoms. [3] Fasciculations can also be caused by deficiencies of magnesium and/or calcium. [6]
A fasciculation, or muscle twitch, is a spontaneous, involuntary muscle contraction and relaxation, involving fine muscle fibers. [1] They are common, with as many as 70% of people experiencing them. [1] They can be benign, or associated with more serious conditions. [1] When no cause or pathology is identified, they are diagnosed as benign ...
Neurology. Multifocal motor neuropathy (MMN) is a progressively worsening condition where muscles in the extremities gradually weaken. The disorder, a pure motor neuropathy syndrome, is sometimes mistaken for amyotrophic lateral sclerosis (ALS) because of the similarity in the clinical picture, especially if muscle fasciculations are present.
Specialty. Neurology, neuromuscular medicine. Neuromyotonia (NMT) is a form of peripheral nerve hyperexcitability that causes spontaneous muscular activity resulting from repetitive motor unit action potentials of peripheral origin. NMT along with Morvan's syndrome are the most severe types in the Peripheral Nerve Hyperexciteability spectrum.
Among the Center's contributions to ALS research have been the 1993 co-discovery of the first genetic mutation linked to cause ALS, SOD1, [11] [12] as well as FUS in 2009 [13] [14] and others linked to familial ALS. In 2015, Les Turner ALS released the campaign, "Freeze ALS", along with 12 ice sculptures around Chicago for ALS Awareness Month ...
Cramp fasciculation syndrome (CFS) is a rare [1] peripheral nerve hyperexcitability disorder. It is more severe than the related (and common) disorder known as benign fasciculation syndrome ; it causes fasciculations , cramps, pain, fatigue, and muscle stiffness similar to those seen in neuromyotonia (another related condition). [ 2 ]
Sharon Hesterlee, Ph.D. (Chief Research Officer)[3] Revenue. $63.7 million (in 2020)[4] Website. www.mda.org. Muscular Dystrophy Association(MDA) is an American nonprofit organizationdedicated to supporting people living with muscular dystrophy, ALS, and related neuromuscular diseases.
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