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2. Stem cell transplantation for articular cartilage repair

   en.wikipedia.org/wiki/Stem_cell_transplantation...

   Stem cells, as a concept, originated as a theory in the 19th century to potentially allow certain tissues to self-renew. There are five types of stem cells, and MSC's are multi-potent, meaning they are cells that have the ability to develop into more than one type of specialized cell. Mesenchymal stem cells were originally discovered and ...

3. Knee cartilage replacement therapy - Wikipedia

   en.wikipedia.org/wiki/Knee_cartilage_replacement...

   Because mesenchymal stem cells may regenerate cartilage, cartilage growth in human knees using autologous cultured mesenchymal stem cells is under research and preliminary clinical use, and appears to be safe as of 2016. [11] An advantage to this approach is that a person's own stem cells are used, avoiding tissue rejection by the immune system ...

4. Stem-cell therapy - Wikipedia

   en.wikipedia.org/wiki/Stem-cell_therapy

   Stem-cell therapy uses stem cells to treat or prevent a disease or condition. [1] As of 2024, the only FDA-approved therapy using stem cells is hematopoietic stem cell transplantation. [2] [3] This usually takes the form of a bone marrow or peripheral blood stem cell transplantation, but the cells can also be derived from umbilical cord blood.

5. Microfracture surgery - Wikipedia

   en.wikipedia.org/wiki/Microfracture_surgery

   One study has shown a success rate of 75 to 80 percent among patients 45 years of age or younger. [21] [22] It is an outpatient procedure and causes only small discomfort. The harder part is the restrictions that are placed on the patient during the post-operative recovery period. This can be a major challenge for many patients.

6. Systemic scleroderma - Wikipedia

   en.wikipedia.org/wiki/Systemic_scleroderma

   The results of a phase-III trial, the Autologous Stem Cell Transplantation International Scleroderma (ASTIS) trial, with 156 patients, were published in 2014. HSCT itself has a high treatment mortality, so in the first year, the survival of patients in the treatment group was lower than the placebo group, but at the end of 10 years, the ...

7. Autologous stem-cell transplantation - Wikipedia

   en.wikipedia.org/wiki/Autologous_stem-cell...

   Autologous stem-cell transplantation is distinguished from allogenic stem cell transplantation where the donor and the recipient of the stem cells are different people. [2] It can be also used as an Assisted reproductive technology to improve the reproductive outcomes. In a first step the bone marrow derived stem cells are mobilized.