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A patch test relies on the principle of a type IV hypersensitivity reaction.. The first step in becoming allergic is sensitization. When skin is exposed to an allergen, the antigen-presenting cells (APCs) – also known as Langerhans cell or Dermal Dendritic Cell – phagocytize the substance, break it down to smaller components and present them on their surface bound major histocompatibility ...
The patch is applied to the skin, usually on the back. The allergens on the patch include latex, medications, preservatives, hair dyes, fragrances, resins, and various metals. [7] Patch testing is used to detect allergic contact dermatitis but does not test for hives or food allergy. [8]
Patch testing helps identify which substances may be causing a delayed-type allergic reaction in a patient and may identify allergens not identified by blood testing or skin prick testing. It is intended to produce a local allergic reaction on a small area of the patient's back, where the diluted chemicals were planted.
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Nickel allergy is typically diagnosed by patch testing – applying a patch with 2.5% (in North America) or 5% (in Europe) nickel sulfate to the upper back and looking for irritation on the skin. [2] As with other causes of allergic contact dermatitis, patches containing several common allergens are typically applied to the back for 48 hours ...
Patch test. Patch testing is a method used to determine if a specific substance causes allergic inflammation of the skin. It tests for delayed reactions. It is used to help ascertain the cause of skin contact allergy or contact dermatitis. Adhesive patches, usually treated with several common allergic chemicals or skin sensitizers, are applied ...
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