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An epinephrine autoinjector (or adrenaline autoinjector, also known by the trademark EpiPen) is a medical device for injecting a measured dose or doses of epinephrine (adrenaline) by means of autoinjector technology. It is most often used for the treatment of anaphylaxis. The first epinephrine autoinjector was brought to market in 1983.
It is recommended that an epinephrine solution be given intramuscularly into the mid anterolateral thigh as soon as the diagnosis is suspected. The injection may be repeated every 5 to 15 minutes if there is insufficient response. [9] A second dose is needed in 16–35% of episodes with more than two doses rarely required. [9]
Examples of affected medications include epinephrine auto-injectors and insulin. [26] Between 2011 and 2016, Mylan was the only competitor on the market and raised the price of EpiPen by almost 400%, and consumers who were forced to pay the cash prices paid reported amounts of $600 or more for a two pack of EpiPen auto-injectors. [27]
The U.S. Food and Drug Administration (FDA) requires autoinjector expiration dates to ensure that the devices never contain less than 90% of the original dose of epinephrine, the study team notes.
“We urge you to amend the current standing regulation to require that epinephrine auto-injectors be included in the emergency medical kit of every flight, as well as engage in regular review of ...
Epinephrine, also known as adrenaline, is a medication and hormone. [10][11] As a medication, it is used to treat several conditions, including anaphylaxis, cardiac arrest, asthma, and superficial bleeding. [8] Inhaled epinephrine may be used to improve the symptoms of croup. [12] It may also be used for asthma when other treatments are not ...
Autoinjector. An autoinjector (or auto-injector) is a medical device for injection of a premeasured dose of a particular drug. Most autoinjectors are one-use, disposable, spring -loaded syringes (prefilled syringes). By design, autoinjectors are easy to use and are intended for self-administration by patients, administration by untrained ...
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