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2. Transfusion-associated graft-versus-host disease - Wikipedia

   en.wikipedia.org/wiki/Transfusion-associated...

   TA-GvHD. Specialty. Hematology. Transfusion-associated graft-versus-host disease (TA-GvHD) is a rare complication of blood transfusion, in which the immunologically competent donor T lymphocytes mount an immune response against the recipient's lymphoid tissue. [1] These donor lymphocytes engraft, recognize recipient cells as foreign and mount ...

3. Graft-versus-host disease - Wikipedia

   en.wikipedia.org/wiki/Graft-versus-host_disease

   Graft-versus-host disease (GvHD) is a syndrome, characterized by inflammation in different organs. GvHD is commonly associated with bone marrow transplants and stem cell transplants. White blood cells of the donor's immune system which remain within the donated tissue (the graft) recognize the recipient (the host) as foreign (non-self).

4. FDA approves Incyte's treatment for chronic graft-versus-host ...

   www.aol.com/news/fda-approves-incytes-treatment...

   Jakafi is approved in the U.S. for treating acute GvHD and is considered a remedy for certain bone marrow and blood d FDA approves Incyte's treatment for chronic graft-versus-host disease Skip to ...

5. Hematopoietic stem cell transplantation - Wikipedia

   en.wikipedia.org/wiki/Hematopoietic_stem_cell...

   Graft-versus-host disease (GvHD) is an inflammatory disease that is unique to allogeneic transplantation. It is an attack by the "new" bone marrow's immune cells against the recipient's tissues. This can occur even if the donor and recipient are HLA-identical because the immune system can still recognize other differences between their tissues.

6. Dr. Jeff Hersh addresses cause, effects and complications of ...

   www.aol.com/dr-jeff-hersh-addresses-cause...

   Graft vs Host Disease occurs when white blood cells produced ... My son received a bone marrow transplant after the chemotherapy wiped out his acute lymphocytic leukemia, and now the doctors say ...

7. Stem-cell therapy - Wikipedia

   en.wikipedia.org/wiki/Stem-cell_therapy

   Another stem-cell therapy, called Prococvhymal, was conditionally approved in Canada in 2012 for the management of acute graft-vs-host disease in children who are unresponsive to steroids. [9] It is an allogenic stem therapy based on mesenchymal stem cells (MSCs) derived from the bone marrow of adult donors. MSCs are purified from the marrow ...

8. Transplant rejection - Wikipedia

   en.wikipedia.org/wiki/Transplant_rejection

   Hyperacute rejection is a form of rejection that manifests itself in the minutes to hours following transplantation. [4] It is caused by the presence of pre-existing antibodies in the recipient that recognize antigens in the donor organ. [5] These antigens are located on the endothelial lining of blood vessels within the transplanted organ and ...

9. Cell therapy - Wikipedia

   en.wikipedia.org/wiki/Cell_therapy

   To lower the risks of transplant, which include graft rejection and graft-versus-host disease (GVHD), allogeneic HSCT must satisfy compatibility at the HLA loci (i.e. genetic matching to reduce the immunogenicity of the transplant). In addition to bone marrow-derived HSCs, the use of alternative sources such as umbilical cord blood (UCB) and ...