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Cannabidiol (CBD) is a phytocannabinoid, one of 113 identified cannabinoids in cannabis plants, along with tetrahydrocannabinol (THC), and accounts for up to 40% of the plant's extract. [18] Medically, it is an anticonvulsant used to treat multiple forms of epilepsy . [ 4 ]
H4CBD (hydrogenated CBD, tetrahydrocannabidiol) is a cannabinoid that was first synthesized by Alexander R. Todd in 1940 derived from the catalytic hydrogenation of cannabidiol. [1] H2-CBD and 8,9-dihydrocannabidiol have also been referred to as "hydrogenated CBD", which may cause confusion.
Cannabinoid receptor antagonist. A cannabinoid receptor antagonist, also known simply as a cannabinoid antagonist or as an anticannabinoid, is a type of cannabinoidergic drug that binds to cannabinoid receptors (CBR) and prevents their activation by endocannabinoids. They include antagonists, inverse agonists, and antibodies of CBRs.
Structure, binding affinity, and potency of popular synthetic cannabinoids and THC Name Year identified by forensics Structural classification Structure CB 1 binding affinity (nM) [87] CB 2 binding affinity (nM) [87] CB 1 EC 50 (nM) [8] CB 2 EC 50 (nM) [8] Δ 9-THC (control phytocannabinoid) Classical cannabinoid 41 ± 2 36 ± 10 250 1157 HU ...
v. t. e. Cannabinoid receptors, located throughout the body, are part of the endocannabinoid system of vertebrates– a class of cell membrane receptors in the G protein-coupled receptor superfamily. [1][2][3][4] As is typical of G protein-coupled receptors, the cannabinoid receptors contain seven transmembrane spanning domains. [5]
Cannabidiolic acid. Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Cannabidiolic acid (CBDA), is a cannabinoid produced in cannabis plants. [1] It is most abundant in the glandular trichomes on the female seedless flowers or more accurately infructescence often colloquially ...
H2CBD (diHydroCBD, partially hydrogenated CBD) are cannabinoids that were first synthesized by Alexander R. Todd in 1940 by catalytic hydrogenation of cannabidiol. [1]The term "H2CBD" can refer to two different chemical compounds that differ by the site of hydrogenation, either saturated on the cyclohexenyl ring (i.e. 1,2-dihydrocannabidiol using the older terpenoid numbering scheme) or ...
Hexahydrocannabinol (HHC) is a hydrogenated derivative of tetrahydrocannabinol (THC). It is a naturally occurring phytocannabinoid that has rarely been identified as a trace component in Cannabis sativa, [1][2] but can also be produced synthetically by firstly acid cyclization of cannabidiol and then hydrogenation of tetrahydrocannabinol.